Administrative Core

行政核心

• 批准号: 10160828
• 负责人: Thomas Patrick Loughran
• 金额: $ 13.97万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-10 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10160828
• 关键词: Accountability; Advisory Committees; Animal Model; Bioinformatics; Biometry; Ceramides; Clinical; Clinical Trials; Collaborations; Ensure; Goals; Institution; Laboratories; Legal patent; Manuscripts; Memorial Sloan-Kettering Cancer Center; Metabolism; Methodology; Modality; Nanotechnology; New Hampshire; Principal Investigator; Productivity; Program Research Project Grants; Progress Reports; Recommendation; Reporting; Resources; Signal Transduction; Sphingolipids; System; United States National Institutes of Health; Universities; Virginia; base; data sharing; galactosylgalactosylglucosylceramidase; glycosylation; lectures; meetings; metabolomics; nanoliposome; performance site; programs; response; success; therapeutic target

PROJECT SUMMARY The overarching goal of the Administrative Core is to oversee and coordinate all scientific, regulatory, administrative and fiscal responsibilities of the Program Project grant. The Administrative Core will accomplish its goal through the following specific aims: 1. Ensure integration of all Projects and Cores by managing all oversight strategies, including coordinating the meetings of the three committees (Executive and the External and Internal Advisory Committees) and implementing the recommendations of these Committees. 2. Realign resources based upon advice from the External and Internal Advisory Committees in collaboration with the Executive Committee (Program Leaders and Project/Core Leaders). 3. Administer and implement the multiple Principal Investigator Plan. 4. Organize the monthly meetings of the Executive Committee, annual meetings of Internal Advisory Committee, and annual meetings of External Advisory Committee. 5. Organize the P01 yearly retreat to assess overall P01 progress, based upon quantitative milestones, and plan and implement next steps making use of the reports from the Internal and External Advisory Committees. 6. Provide governance and accountability for the CAV trial 7. Provide fiscal accountability via coordination with institutional and NCI staff. 8. Document productivity of all Projects and Cores, as defined by discrete endpoints such as manuscripts, filed provisional patent applications, and invited lectures. 9. Prepare all progress reports and responses to External and Internal Advisory Committees. 10. Coordinate and oversee all scientific, regulatory, administrative, and fiscal interactions between the University of Virginia, Eastern Carolina University, Memorial Sloan Kettering Cancer Center, University of New Hampshire, and Penn State University. 11. Ensure accountability and governance of all biostatistics, bioinformatics, and “-omic” methodology across all projects and cores. 12. Coordinate Data Sharing modalities between Institutions, NIH, Nanotechnology Characterization Laboratory (NCL), and the public. 13. Coordinate the monthly Core presentations to the Executive Committee that will include descriptions of the active and pending requests for support from each Project.

项目概要 行政核心的总体目标是监督和协调所有科学、监管、 行政核心将完成该计划项目拨款的行政和财政职责。 其目标通过以下具体目标实现： 1. 通过管理所有监督策略，确保所有项目和核心的整合，包括 协调三个委员会（执行委员会和外部及内部咨询委员会）的会议 委员会）并实施这些委员会的建议。 2. 根据外部和内部咨询委员会的建议重新调整资源 与执行委员会（计划领导者和项目/核心 领导）。 3.管理和实施多重首席研究员计划。 4、组织执行委员会月度会议、内部委员会年会 咨询委员会，以及外部咨询委员会的年度会议。 5. 组织 P01 年度务虚会，根据定量评估整体 P01 进展 里程碑，并利用内部和外部的报告来计划和实施后续步骤 外部咨询委员会。 6. 为 CAV 试验提供治理和问责 7. 通过与机构和 NCI 工作人员协调，提供财政问责制。 8. 记录所有项目和核心的生产力，由离散端点定义，例如 手稿、提交专利申请和特邀讲座。 9. 准备所有进度报告以及对外部和内部咨询委员会的答复。 10. 协调和监督各部门之间的所有科学、监管、行政和财政互动 弗吉尼亚大学、东卡罗来纳大学、纪念斯隆凯特琳癌症中心、 新罕布什尔大学和宾夕法尼亚州立大学。 11. 确保所有生物统计学、生物信息学和“-omic”的问责制和治理 跨所有项目和核心的方法论。 12. 协调机构、NIH、纳米技术表征之间的数据共享模式 实验室（NCL）和公众。 13. 协调向执行委员会提交的每月核心报告，其中包括说明 每个项目的有效和待处理的支持请求。