CTSA Graduate Program

CTSA研究生计划

基本信息

批准号：
10159335
负责人：
DAVID M KENT
金额：
$ 82.7万
依托单位：
TUFTS UNIVERSITY BOSTON
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-05-01 至 2023-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10159335
关键词：
Academic Medical Centers Active Learning Area Biomedical Research Biotechnology Boston Budgets Career Choice Clinical Clinical Competence Clinical Research Clinical Sciences Clinical Trials Collaborations Comparative Effectiveness Research Development Development Plans Device or Instrument Development Doctor of Philosophy Environment Exposure to Face Failure Funding Future Genus Mentha Growth Health Health Policy Human Individual Industry Infrastructure Institutes Institution Massachusetts Mentors Modernization Nutritional Science Productivity Program Development Recording of previous events Research Research Training Schools Science Science Policy Scientist Students TNFSF15 gene Technology The Jackson Laboratory Training Translational Research Translations United States National Institutes of Health Universities base biomedical scientist career career development community engagement drug development economic evaluation experience externship industry partner innovation next generation population based programs real world application recruit retention rate skills success translational pipeline trend

项目摘要

The success of the biomedical research enterprise depends upon a robust pipeline of scientists with diverse expertise, well-trained in the core competencies of clinical and translational science (CTS). Major threats to this pipeline include the mismatch between the needs of the modern research workforce and the narrow training received in most biomedical PhD programs. Additionally, clinicians face an increasingly difficult transition to stable career development funding without rigorous research training. For almost two decades, the Tufts Sackler CTS Graduate Program, the training core of Tufts CTSI, has successfully trained clinician-scientists across the spectrum of translational research, emphasizing later stages of translation (T2-T4) with a broad impact on health. With this CTSA renewal, we will substantially expand and enhance our TL1 Program commensurate to the growth of Tufts CTSI to meet the larger training needs, building on the history of excellence in our MS/PhD CTS Program, by the following aims: AIM 1) we will provide rigorous training in the core competencies of CTS to a diverse set of scholars, including more PhD-trained biomedical scientists. We will leverage the broadened partnerships of the Tufts CTSI, including the Tufts University Sackler School, the Jackson Laboratory, the Massachusetts Institute of Technology (MIT), and Northeastern University, and a strengthened connection to the Tufts Friedman School of Nutrition Science and Policy. AIM 2) we will expand the mentoring and research experiences to enhance the individual development plans of TL1 fellows and all CTS Graduate Program students. This will include offering four specialized TL1 tracks, emphasizing institutional strengths: Comparative Effectiveness Research; One Health; Drug and Device Development; Health Policy. We will also establish innovative research externships – based at partner institutions and around Boston’s rich biotech hub – and new seminars and studios on topics critical for success in the modern translational workforce, including stakeholder/community engagement, team science, rigor and transparency, academic-industry partnerships, and clinical trial innovations. We will equip clinician-scientists and biomedical PhD scientists with the skills and experience necessary to succeed in an environment that has shifted to broadly-engaged, team-based translational research.

生物医学研究企业的成功取决于拥有多元化科学家的强大渠道。专业知识，在临床和转化科学（CTS）的核心能力方面训练有素。对此的主要威胁。管道包括现代研究人员的需求与狭隘的培训之间的不匹配在大多数生物医学博士学位课程中获得。近二十年来，塔夫茨大学在没有严格的研究培训的情况下获得了稳定的职业发展资金。萨克勒 CTS 研究生项目是塔夫茨 CTSI 的培训核心，已成功培训临床医生科学家跨越翻译研究的各个领域，强调翻译的后期阶段（T2-T4）通过此次 CTSA 更新，我们将大幅扩展和增强我们的 TL1 计划。与塔夫茨 CTSI 的发展相称，以满足更大的培训需求，建立在历史的基础上卓越的 MS/PhD CTS 计划，通过以下目标：AIM 1) 我们将提供严格的培训将 CTS 的核心能力介绍给不同的学者，包括更多受过博士学位的生物医学科学家。将利用塔夫茨 CTSI 扩大的合作伙伴关系，包括塔夫茨大学萨克勒学院、杰克逊实验室、麻省理工学院 (MIT) 和东北大学，以及加强与塔夫茨弗里德曼营养科学与政策学院的联系 AIM 2) 我们将扩大。指导和研究经验，以增强 TL1 研究员和所有人员的个人发展计划 CTS 研究生课程的学生将包括提供四个专门的 TL1 课程，强调机构优势：比较有效性研究；药物和设备开发；卫生政策。我们还将在合作机构及周边地区建立创新研究实习项目。波士顿丰富的生物技术中心 - 以及新的研讨会和工作室，主题对现代成功至关重要转化型员工队伍，包括利益相关者/社区参与、团队科学、严谨性和透明度，我们将为临床科学家和生物医学提供学术与工业合作伙伴关系以及临床试验创新。拥有在已转变的环境中取得成功所需的技能和经验的博士科学家广泛参与、基于团队的转化研究。