Northwestern University Clinical and Translational Science Institute (NUCATS)

西北大学临床与转化科学研究所 (NUCATS)

• 批准号: 10158665
• 负责人: Richard D'Aquila
• 金额: $ 22.63万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-12 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10158665
• 关键词: Achievement; Address; Adopted; Adult; Analgesics; Applied Research; Area; Arts; Automobile Driving; Biomedical Research; Biometry; Biotechnology; Businesses; Cancer Center; Cardiology; Caring; Chemistry; Chicago; Child; Child Health; Childhood; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communities; Community Physician; Comprehensive Cancer Center; Data Science; Dermatology; Development; Diagnostic; Ecosystem; Education; Engineering; Environment; Evaluation; Evolution; Fostering; Funding; Future; Goals; Health; Healthcare; High Density Lipoproteins; Hospitals; Housing; Human; Hypersensitivity; Immunology; Individual; Industrialization; Informatics; Information Technology; Infrastructure; Institutes; Institution; Institutional Policy; Institutional Review Boards; Intensive Care; Interdisciplinary Study; Lead; Learning; Letters; Location; Longevity; Lymphoma; Marketing; Maternal-fetal medicine; Medical Device; Medicine; Methods; Mission; Nanotechnology; Neurology; Neurosurgical Procedures; Nursing Faculty; Office Management; Patient Outcomes Assessments; Pediatric Hospitals; Pharmacology; Physical Medicine; Physical Rehabilitation; Physiology; Population Sciences; Preventive Medicine; Process; Public Health; Rehabilitation therapy; Reporting; Reproducibility; Research; Research Infrastructure; Research Methodology; Research Personnel; Resources; Role; Schools; Science; Speed; Surveys; System; Testing; Therapeutic; Training; Training Programs; Translational Research; Translations; United States National Institutes of Health; Universities; Urology; Vision; Work; arm; base; cancer clinical trial; care systems; clinical care; clinical encounter; clinical practice; college; commercialization; design; digital; drug development; experimental study; health care delivery; improved; innovation; materials science; medical schools; nanobiosensor; news; novel; outreach; particle; patient population; precision medicine; programs; research study; surgery outcome; therapeutic development; tool; undergraduate student

Contact PD/PI: LLOYD-JONES, DONALD M ABSTRACT. The Northwestern University Clinical and Translational Sciences Institute (NUCATS) serves as an integrated hub to advance Clinical and Translational Science (CTS) at three distinct scales: locally, at Northwestern University (NU) and our 3 nationally-renowned clinical partners; regionally, across Chicago and in collaboration with the other two Chicago CTSA hubs and our many community stakeholder partners; and, nationally, through our active participation in the CTSA Consortium. By leveraging continuous CTSA funding since 2008, as well as substantial financial and in-kind support from NU and our partners, NUCATS has succeeded at all three scales, evolving into a mature, balanced, highly-functioning CTSA with a broad portfolio of leading-edge programs spanning T0 through T4. Looking to the future, we recognize that there continue to be exciting strategic opportunities for innovation and improvement, and NUCATS is not afraid to experiment upon itself to achieve our mission of speeding transformative research discoveries to patients and the population, in order to improve human health. We will build on this legacy through five broad-based Global Objectives, which focus on: expanding and further integrating research into clinical care systems and processes, with the ultimate goal that every clinical encounter can be an opportunity for research participation, precision medicine, and learning to improve human health for all; accelerating local, regional, and national CTS by enhancing our existing integrated digital research infrastructure to develop and apply new, leading-edge informatics and data science tools to catalyze research, education, collaboration, engagement, evaluation, and dissemination; broadening our community and stakeholder engagement and advance team science to enable high-functioning, stakeholder-engaged, multi-disciplinary research teams that have impact across the spectrum of CTS; developing, demonstrating, disseminating, and adopting innovative and sustainable CTS methods and processes to accelerate translation and foster a culture of rigor, reproducibility, evaluation, and continuous improvement across the CTSA consortium; and innovating, testing, and disseminating novel training programs to cultivate, equip, and empower the diverse translational research workforce of tomorrow. We propose to leverage CTSA funding to address key strategic opportunities and critical barriers to CTS, not only at NUCATS, but across Chicagoland and the CTSA consortium. In doing so, we anticipate that NUCATS will continue be a central player in the ongoing evolution of the role of CTSA Program in accelerating CTS to improve human health. Page 236 Project Summary/Abstract Contact PD/PI: LLOYD-JONES, DONALD M

联系PD/PI：Lloyd-Jones，Donald M 抽象的。西北大学临床和转化科学研究所（NUCATS）作为 一个集成枢纽，以三种不同的尺度推进临床和转化科学（CTS）：在本地，在 西北大学（NU）和我们的3个全国著名临床伙伴；在芝加哥的区域上， 与其他两个芝加哥CTSA枢纽和我们许多社区利益相关者合作伙伴合作；和， 在全国范围内，通过我们积极参加CTSA财团。通过利用连续的CTSA资金 自2008年以来，NU和我们的合作伙伴的大量财务和实物支持， 在所有三个尺度上都取得了成功，演变成一个成熟，平衡，高功能的CTSA，并具有广泛的投资组合 跨越T0至T4的领先程序。展望未来，我们认识到 成为创新和改进的令人兴奋的战略机会，核心不怕试验 本身是为了实现我们的使命，即向患者和 人口，以改善人类健康。我们将通过五个基于五个广泛的全球范围内建立这一遗产 目标，重点是：扩大和进一步将研究扩展到临床护理系统和 过程，最终目标是每次临床遭遇都可以成为研究参与的机会， 精确医学，并学习改善所有人的人类健康；加速本地，区域和国家CTS 通过增强我们现有的综合数字研究基础架构，以开发和应用新的，领先的边缘 信息学和数据科学工具可促进研究，教育，协作，参与，评估以及 传播；扩大我们的社区和利益相关者的参与和进步团队科学以实现 高功能，利益相关者参与的，多学科的研究团队，在整个人中有影响 CTS频谱；开发，展示，传播和采用创新和可持续的CTS 加速翻译并培养严格，可重复性，评估和培养的方法和过程 整个CTSA财团的持续改进；和创新，测试和传播小说 培训计划，以培养，装备和授权明天的多样化的转化研究劳动力。 我们建议利用CTSA资金来解决CTS的关键战略机遇和关键障碍，而不是 仅在核心，但遍布芝加哥和CTSA联盟。在这样做时，我们预计会核 将继续是CTSA计划在加速CTS中的角色持续发展中的核心参与者 改善人类健康。 第236页 项目摘要/摘要 联系PD/PI：Lloyd-Jones，Donald M