Development of novel therapeutic strategies in head and neck squamous cell carcinoma based on microRNA-mediated cancer pathways

基于microRNA介导的癌症通路开发头颈鳞状细胞癌新治疗策略

• 批准号: 15K10801
• 负责人: SEKI NAOHIKO
• 金额: $ 3.08万
• 依托单位: Chiba University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K10801/
• 关键词: マイクロRNA; 頭頸部扁平上皮癌; 癌抑制遺伝子; インテグリン; 発現プロファイル; 機能性RNA; 癌抑制型マイクロRNA; 癌促進型マイクロRNA; 治療抵抗性; EGFR; c-MET; MET; シグナル伝達; 受容体

项目成果

Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma

• DOI: 10.1038/jhg.2015.120
• 发表时间: 2016-02-01
• 期刊: JOURNAL OF HUMAN GENETICS
• 影响因子: 3.5
• 作者: Fukumoto, Ichiro;Kikkawa, Naoko;Seki, Naohiko
• 通讯作者: Seki, Naohiko

MicroRNA expression signature of oral squamous cell carcinoma: functional role of microRNA-26a/b in the modulation of novel cancer pathways.

• DOI: 10.1038/bjc.2015.19
• 发表时间: 2015-03-03
• 期刊: BRITISH JOURNAL OF CANCER
• 影响因子: 8.8
• 作者: Fukumoto, I.;Hanazawa, T.;Kinoshita, T.;Kikkawa, N.;Koshizuka, K.;Goto, Y.;Nishikawa, R.;Chiyomaru, T.;Enokida, H.;Nakagawa, M.;Okamoto, Y.;Seki, N.
• 通讯作者: Seki, N.

Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs.

• DOI: 10.18632/oncotarget.16327
• 发表时间: 2017-05-02
• 期刊: Oncotarget
• 作者: Koshizuka K;Nohata N;Hanazawa T;Kikkawa N;Arai T;Okato A;Fukumoto I;Katada K;Okamoto Y;Seki N
• 通讯作者: Seki N