Development of the objective diagnostic method using the specific serum antibody titer on peri-implantitis.

开发使用特异性血清抗体滴度对种植体周围炎进行客观诊断的方法。

• 批准号: 23593062
• 负责人: YONEDA Satoshi
• 金额: $ 3.08万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23593062/
• 关键词: インプラント周囲炎; マイクロバイオーム解析

This study was performed on 20 implants of 16 subjects. The number of the implant with peri-implantitis which have the bone defect more than 2mm on X-ray photograph was nine. In the examination of periodontopathic bacteria, it is not concerned with the peri-implantitis, but T.forsythesis was detected by high frequency.Furthermore, microbiome analysis was conducted for 11 implants (7 peri-implantitis) of nine subjects, and nine natural teeth. As a result, with periodontosis and peri-implantitis, the rate of G.Alkalibacterium, G.Halomonas, G.Treponema, and G.Acidaminococcus is high. Especially G.Acidaminococcus is notably high with the peri-implantitis.

这项研究针对 16 名受试者的 20 个种植体进行。 X射线照片上骨缺损超过2mm、患有种植体周围炎的种植体有9个。在牙周病细菌检查中，与种植体周围炎无关，但高频率检出T.forsythesis。此外，对9名受试者的11颗种植体（7颗种植体周围炎）和9颗天然牙进行了微生物组分析。因此，在牙周病和种植体周围炎中，G.碱杆菌、G.盐单胞菌、G.密螺旋体和G.酸氨基球菌的比例很高。尤其是G.Acidaminococcus，在种植体周围炎中尤其明显。