Development of Catheter therapy for ventricular sqptal perforation

心室间隔穿孔导管治疗的进展

• 批准号: 23592033
• 负责人: USUI Akihiko
• 金额: $ 3.24万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592033/
• 关键词: 心筋梗塞; 心室中隔穿孔; カテーテル治療; 心臓手術

We developed a catheter therapy for ventricular septum perforation (VSP) by using a stent-graft placed in the left ventricle. we adapt a net type stent which is knitted by a Nytinol thread. As an initial model, we made a cone-shaped stent-graft but it did not fit with papillary muscles. We changed the design of the stent-graft as a dissymmetry. It covered only with the septum but a pressure power of the septum side particularly the septum base side was weak even with the improved model.We made delivery sheath for direct insertion via the apex and developed an insertion method by using peal off system. We insert a stent-graft into a rubber heart model by using this delivery system. The stent graft can be inserted via the left ventricle apex and has it as a design preserving the directionality by fixing it in the apex. The design decision of the stent-graft which does not affect cardiac function is difficult and remains in the completion of a trial

我们开发了一种通过使用放置在左心室的覆膜支架治疗室间隔穿孔（VSP）的导管疗法。我们采用由Nytinol线编织而成的网状支架。作为初始模型，我们制作了一个锥形覆膜支架，但它不适合乳头肌。我们改变了覆膜支架的设计，使其不对称。虽然仅覆盖了隔膜，但即使是改良型号，隔膜侧特别是隔膜基部侧的压力力也较弱。我们制作了通过顶端直接插入的输送鞘，并开发了使用剥离系统的插入方法。我们使用这种输送系统将覆膜支架插入橡胶心脏模型中。覆膜支架可以通过左心室心尖插入，并通过将其固定在心尖来保持方向性的设计。不影响心脏功能的覆膜支架的设计决策很困难，仍需完成试验

项目成果

心臓・血管吻合に必要な新しいデバイスの開発医療現場での開発・研究課題の実例

开发心脏血管吻合术所需的新设备 医疗环境中的开发和研究问题示例

• 发表时间: 2012
• 作者: 碓氷章彦

心臓・血管吻合に必要な新しいデバイスの開発

开发心脏血管吻合术所需的新装置

• 发表时间: 2012
• 作者: 碓氷章彦