Significance of meso-pancreatoduodenum for en bloc resection of pancreatic head carcinoma

胰十二指肠系膜在胰头癌整块切除中的意义

• 批准号: 23592005
• 负责人: KITAGAWA Hirohisa
• 金额: $ 3.58万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592005/
• 关键词: 膵頭部癌; Mesopancreatoduodenum; 腎筋膜前葉; 後方組織への浸潤; リンパ行性進展; 直接浸潤; 上腸間膜動脈神経叢; 膵頭神経叢; mesopancreatoduodenum; 下膵十二指腸動脈; 後腹膜腔; リンパ管; 神経線維; mesopancreas; 癒合筋膜

Resection of lymphatic basin and clearance of direct invasion are required for curative resection of pancreatic carcinoma. The anterior renal fascia acts as a barrier against retropancreatic invasion. The principle underlying our surgical strategy for resectable pancreatic head carcinoma is total excision of the lymphatic basin of the pancreatic head, which is termed meso-pancreatoduodenum (meso-pd). Our meso-pd concept refers to the mesentery of the pancreatic head and the duodenum, which is a firm and well-vascularized perineural lymphatic layer located dorsal to the pancreas that reaches behind the mesenteric vessels. The meso-pd is fan-shaped and its trunk is the inferior pancreatoduodenal artery, which is a tributary of the SMA. Therefore, a total meso-pd resection was performed with respect to the PLX surrounding the SMA and including the anterior renal fascia.

胰腺癌的根治性切除需要切除淋巴管并清除直接侵犯。肾前筋膜充当抵抗胰后侵袭的屏障。我们可切除胰头癌手术策略的基本原理是完全切除胰头淋巴盆地，称为胰十二指肠系膜（meso-pd）。我们的 meso-pd 概念是指胰头和十二指肠的肠系膜，它是位于胰腺背侧、到达肠系膜血管后面的坚固且血管丰富的神经周围淋巴层。中动脉呈扇形，其主干为胰十二指肠下动脉，为 SMA 的分支。因此，对 SMA 周围的 PLX 进行了全中段切除，包括前肾筋膜。

项目成果

進行膵頭部癌に対するTotal mesopancreatic excisionを幹とした集学的治療

以全胰系膜切除为主的多学科治疗晚期胰头癌

• 发表时间: 2012
• 作者: 北川裕久

Significance of en bloc resection with the anterior renal fascia for adenocarcinoma of the left pancreas

肾前筋膜整块切除术治疗左胰腺腺癌的意义

• 作者: H Kitagawa

【膵癌外科切除成績の向上を目指した治療戦略】Mesopancreatoduodenum (Meso-PD)に重点を置いた膵頭部癌に対する治療戦略

[以改善胰腺癌手术切除效果为目标的治疗策略]以胰十二指肠系膜（Meso-PD）为中心的胰头癌治疗策略

• 发表时间: 2013
• 作者: 北川裕久; 田島秀浩; 中川原寿俊
• 通讯作者: 中川原寿俊

Complete total mesopancreatic excision including superior mesenteric artery and vein for locally advanced pancreatic head carcinomas.

对局部晚期胰头癌进行完整的全胰系膜切除，包括肠系膜上动脉和静脉。

• 发表时间: 2012
• 作者: H Kitagawa

the role of the retropancreatic fascia against the retropancreatic infiltration of the pancreatic carcinoma

胰后筋膜对胰腺癌胰后浸润的作用

• 发表时间: 2012
• 作者: H Kitagawa