Study on the Proportion of Intravenously Administered Drugs Excreted into the Stomach in Forensic Autopsy Cases
法医尸检案件中静脉给药药物排泄入胃的比例研究
基本信息
- 批准号:23590864
- 负责人:
- 金额:$ 1.25万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2011
- 资助国家:日本
- 起止时间:2011 至 2013
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
I demonstrated that: (1) in both basic therapeutic agents that were intravenously administered during the course of unsuccessful medical treatments and intravenously self-administered methamphetamine, a relatively good positive correlation was observed between the levels of those substances in the blood and stomach contents; (2) the average stomach content-to-blood ratio was 9.59 for basic agents, 0.38 for acidic agents and 16.1 for methamphetamine; (3) up to 10 mg of methamphetamine can accumulate in the stomach; and (4) the stomach-to-blood methamphetamine ratio is significantly affected by the particular mechanism of death. The stomach content-to-blood ratio for basic drugs may serve as a criterion for discriminating whether a drug was administered orally or intravenously.
我证明:(1)在治疗失败期间静脉注射的基础治疗药物和自行静脉注射的甲基苯丙胺中,血液中这些物质的水平与胃内容物之间都观察到了较好的正相关性; (2)碱性药剂的平均胃内容物与血液的比率为9.59,酸性药剂的平均胃内容物与血液的比率为0.38,甲基苯丙胺的平均胃内容物与血液的比率为16.1; (3)甲基苯丙胺在胃中最多可积聚10毫克; (4)胃与血液中甲基苯丙胺的比率受特定死亡机制的显着影响。碱性药物的胃内容物与血液的比率可以作为区分药物是口服还是静脉注射的标准。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
死亡過程が静脈内投与されたメタンフェタミンの胃内容/血液濃度比に及ぼす影響
死亡过程对静脉注射甲基苯丙胺胃内容物/血液浓度比的影响。
- DOI:
- 发表时间:2013
- 期刊:
- 影响因子:0
- 作者:守屋文夫;吉留敬;宮石智
- 通讯作者:宮石智
A large proportion of intravenously administered methamphetamine is excreted into the stomach
静脉注射的冰毒很大一部分被排泄到胃中
- DOI:
- 发表时间:2014
- 期刊:
- 影响因子:2.2
- 作者:Fumio Moriya;Kei Yoshitome;Satoru Miyaishi
- 通讯作者:Satoru Miyaishi
A LARGE PROPORTION OF INTRAVENOUSLY ADMINISTERED METHAMPHETAMINE IS EXCRETED INTO THE STOMACH
静脉注射的甲基苯丙胺的大部分被排泄到胃中
- DOI:10.1007/s11419-013-0207-4
- 发表时间:2014
- 期刊:
- 影响因子:0
- 作者:FUMIO MORIYA; KEI YOSHITOME; SATORU MIYAISHI
- 通讯作者:SATORU MIYAISHI
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MORIYA Fumio其他文献
MORIYA Fumio的其他文献
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{{ truncateString('MORIYA Fumio', 18)}}的其他基金
Forensic Toxicological Study on Excretion of Intravenously Administered Drugs into the Stomach
静脉给药药物胃排泄的法医毒理学研究
- 批准号:
26460893 - 财政年份:2014
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Clinical and Forensic Toxicological Studies on Endogenous Gamma-Hydroxybutyric Acid in Body Fluids and Tissues
体液和组织中内源性γ-羟基丁酸的临床和法医毒理学研究
- 批准号:
19590675 - 财政年份:2007
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Forensic and clinical toxicologic studies on blood cyanide concentrations in fire victims
火灾受害者血液氰化物浓度的法医和临床毒理学研究
- 批准号:
13670426 - 财政年份:2001
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Interpretation of drug concentrations in pericardial fluid, cerebrospinal fluid and vitreous humor
心包液、脑脊液和玻璃体液中药物浓度的解读
- 批准号:
11670419 - 财政年份:1999
- 资助金额:
$ 1.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
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- 资助金额:
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