Study on nutritional property and diabetes prevention effects of Silkworm pupae (Bombyx mori)

蚕蛹营养特性及预防糖尿病作用的研究

• 批准号: 23500947
• 负责人: TOMOTAKE Hiroyuki
• 金额: $ 3.08万
• 依托单位: Iida Women's Junior College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23500947/
• 关键词: 蚕サナギ; 糖質分解酵素阻害作用; 血糖上昇抑制作用; 血糖上昇抑制; アンギオテンシンI変換酵素; 溶解性; 脱脂; イナゴ; 消化性; ラジカル補足活性; 抗菌活性; 成分分析; 二糖類分解酵素阻害活性

This study was performed to evaluate the nutritional value and bioactive component of silkworm pupase (Bombyx mori) and the alfa-glucosidase inhibitory effect of water extracts of that. Hot water extract of silkworm pupase inhibited angiotensin-converting enzyme, porcin panreatic alfa-glucosidase and an increase of blood glucose level in rats. Phosphate buffer extract of silkworm pupase has DPPH radical scavenging activity. Methanol extract of silkworm pupase has antibacterial activity against Staphylococcus aureus. These results suggest that silkworm pupase is a new source of bioactive components and alfa-glucosidase inhibitor.

本研究旨在评价蚕蛹酶（Bombyx mori）的营养价值和生物活性成分及其水提取物的α-葡萄糖苷酶抑制作用。蚕蛹酶热水提取物抑制血管紧张素转换酶、猪胰α-葡萄糖苷酶和大鼠血糖水平升高。蚕蛹酶磷酸缓冲提取物具有DPPH自由基清除活性。蚕蛹酶的甲醇提取物对金黄色葡萄球菌具有抗菌活性。这些结果表明蚕蛹酶是生物活性成分和α-葡萄糖苷酶抑制剂的新来源。

项目成果

Burdock fermented by Aspergillus awamori elevates cecal Bifidobacterium, and reduces fecal deoxycholic acid and adipose tissue weight in rats fed a high-fat diet

泡盛曲霉发酵的牛蒡可提高盲肠双歧杆菌水平，并降低高脂饮食大鼠粪便脱氧胆酸和脂肪组织重量

• 发表时间: 2013
• 作者: Okazaki Y; Sitanggang NV; Sato S; Ohnishi N; Inoue J; Iguchi T; Watanabe T; Tomotake H; Harada K; Kato N
• 通讯作者: Kato N

Treatment with buckwheat bran extract prevents the elevation of serum triglyceride levels and fatty liver and in KK-Ay mice

荞麦麸提取物治疗可防止 KK-Ay 小鼠血清甘油三酯水平升高和脂肪肝

• 发表时间: 2014
• 作者: Hosaka T; Sasaga S; Yamasaka Y; Nii Y; Edazawa K; Tsutsumi R; Shuto E; Okahisa N; Iwata S; Tomotake T; Sakai T
• 通讯作者: Sakai T

蚕サナギの1-デオキシノジリマイシン含量および糖質分解酵素阻害作用

蚕蛹中1-脱氧野尻霉素含量及碳水化合物降解酶抑制作用

• 发表时间: 2014
• 作者: 友竹浩之;片桐 充昭
• 通讯作者: 片桐 充昭

高圧加熱処理がそばタンパク質の溶解性と抗原性に及ぼす影響

高压热处理对荞麦蛋白溶解度和抗原性的影响

• 发表时间: 2012
• 作者: 友竹浩之; 柴本むつ美; 富口由紀子
• 通讯作者: 富口由紀子

Tempe consumption modulates fecal secondary bile acids, mucins, immunoglobulin A, enzyme activities, and cecal microflora and organic acids in rats

Tempe 摄入可调节大鼠粪便次级胆汁酸、粘蛋白、免疫球蛋白 A、酶活性以及盲肠微生物区系和有机酸

• DOI: 10.1007/s11130-013-0357-x
• 发表时间: 2013
• 作者: Utama Z; Okazaki Y; Tomotake H; Kato N
• 通讯作者: Kato N