Regulation of normal and malignant hematopoiesis by protein glycosylation with O-GlcNAc

O-GlcNAc 蛋白糖基化对正常和恶性造血的调节

• 批准号: 17K09909
• 负责人: NAKAJIMA HIDEAKI
• 金额: $ 2.91万
• 依托单位: Yokohama City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2017
• 资助国家: 日本
• 起止时间: 2017-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K09909/
• 关键词: 造血幹細胞; OGT; O-GlcNAc; ミトコンドリア; マイトファジー; O-GlcNAc修飾; 血球分化; 造血器腫瘍; O結合型β-N-アセチルグルコサミン

项目成果

Yokohama Cooperative Study Group for Hematology (YACHT).: Impact of treatment-related weight changes from diagnosis to hematopoietic stem-cell transplantation on clinical outcome of acute myeloid leukemia.

横滨血液学合作研究小组（YACHT）：从诊断到造血干细胞移植的治疗相关体重变化对急性髓系白血病临床结果的影响。

• 发表时间: 2019
• 期刊: Int J Hematol.
• 作者: Ando T;Fujisawa S;Teshigawara H;Ogusa E;Ishii Y;Miyashita K;Motohashi K;Miyazaki T;Tachibana T;Hagihara M;Matsumoto K;Tanaka M;Hashimoto C;Koharazawa H;Fujimaki K;Taguchi J;Fujita H;Kanamori H;Yamazaki E;Nakajima H
• 通讯作者: Nakajima H

O-GlcNAcylation is critical for mitochondrial dynamics in hematopoietic stem cells

O-GlcNAc 酰化对于造血干细胞的线粒体动力学至关重要

• 发表时间: 2018
• 作者: Koichi Murakami;Daisuke Kurotaki;Wataru Kawase;et al.
• 通讯作者: et al.

Salvage and bridging to allogeneic hematopoietic cell transplantation with ponatinib in patients with relapsed or refractory Philadelphia chromosome-positive leukemia

普纳替尼对复发或难治性费城染色体阳性白血病患者的挽救和桥接同种异体造血细胞移植

• DOI: 10.1007/s12185-018-02571-0
• 发表时间: 2018
• 期刊: International Journal of Hematology
• 影响因子: 2.1
• 作者: Tachibana Takayoshi;Koyama Satoshi;Andou Taiki;Ishiyama Yasufumi;Tanaka Masatsugu;Nakajima Hideaki;Kanamori Heiwa
• 通讯作者: Kanamori Heiwa

Successful treatment of systemic Erdheim-Chester disease with interferon-alpha.

用干扰素-α成功治疗系统性埃尔德海姆-切斯特病。

• 发表时间: 2019
• 作者: Mao Wakamatsu;Takuya Miyazaki;Ayako Matsumura;Haruka Teshigawara;Hiroshi Teranaka;Satoshi Koyama;Hiroyuki Takahashi;Hiroyoshi Kunimoto;Makiko Enaka;Daisuke Kamimura;Maki Hagihara;Kenji Matsumoto;Etsuko Yamazaki;Hideaki Nakajima
• 通讯作者: Hideaki Nakajima

Guest editorial: Hematopoietic stem cells.

客座社论：造血干细胞。

• DOI: 10.1007/s12185-017-2267-4
• 发表时间: 2017
• 期刊: Int J Hematol.
• 作者: Kunimoto H;Nakajima H.;Nakajima H
• 通讯作者: Nakajima H