Development of multi-functional nano carbons for bio applications

开发用于生物应用的多功能纳米碳

• 批准号: 21791929
• 负责人: ABE Shigeaki
• 金额: $ 2.66万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21791929/
• 关键词: カーボンナノチューブ; フラーレン; 体内動態; 歯科用材料・歯科理工学; 歯科用材料; 生体適合性

In this study, visualization of biodistribution of nano carbon materials, such as fullerene and carbon nanotube(CNT), was investigated to elucidate the biocompatibility. To administer and visualize the biodistribution in mice, bio-injectable nanocarbon materials dispersion was prepared through chemical modification. The injected materials were reached some organs and then detected by some electron microscopic observation. Their cytotoxicity were also determined.

在本研究中，对富勒烯和碳纳米管（CNT）等纳米碳材料的生物分布进行可视化研究，以阐明其生物相容性。为了管理和可视化小鼠体内的生物分布，通过化学修饰制备了生物可注射纳米碳材料分散体。注射的材料到达一些器官，然后通过一些电子显微镜观察进行检测。还测定了它们的细胞毒性。

项目成果

Spectral narrowing of UV-visible absorption and emission spectra of anthracene-derivatives in b-cyclodextrin nanocavity : Effects of host/guest stoichiometry

b-环糊精纳米腔中蒽衍生物的紫外-可见吸收和发射光谱的光谱变窄：主体/客体化学计量的影响

• 发表时间: 2012
• 影响因子: 0.7
• 作者: S.

Density Functional Theory(DFT) Study on the water clusters on Graphene Chip

石墨烯芯片上水团簇的密度泛函理论（DFT）研究

• 发表时间: 2011
• 作者: S. Abe; Y. Nagoya; F. Watari;H. Tachikawa
• 通讯作者: H. Tachikawa

Biodistribution and Biocompatibility of poly(lactic acid)-coated SiO2 particles

聚乳酸包覆SiO2颗粒的生物分布和生物相容性

• 发表时间: 2011
• 作者: S.Abe; A.Sasaki; N.Iwadera; T.Akasaka; M.Uo; F.Watari
• 通讯作者: F.Watari

A Direct ab-initio MD study on the interaction of hydroperoxy radical(HOO)with Water Molecules

氢过氧自由基(HOO)与水分子相互作用的直接从头MD研究

• 发表时间: 2010
• 作者: Hiroto Tachikawa; Shigeaki Abe
• 通讯作者: Shigeaki Abe

Internal distribution of micro-/nano-sized ceramics and metals particles in mice

微/纳米陶瓷和金属颗粒在小鼠体内的分布

• 发表时间: 2010
• 作者: Shigeaki Abe; Ikuhiro Kida; Mitsue Esaki; Nobuki Iwadera; Mami Mutoh; Chika Koyama; Tsukasa Akasaka; Motohiro Uo; Yoshinori Kuboki; Manabu Morita; Yoshinori Sato; Koichi Haneda; Tetsu Yonezawa; Balachan dran Jeyadevan; Kazuyuki Tohji; Fumio Watari
• 通讯作者: Fumio Watari