The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.

基质 Hic-5 通过赖氨酰氧化酶诱导和基质重塑对结直肠癌肿瘤发生的影响。

• 批准号: 16K10553
• 负责人: Omoto Tomokastu
• 金额: $ 3万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K10553/
• 关键词: Hic-5; 大腸がん; がん関連線維芽細胞; 細胞外微小環境制御; 大腸癌; 癌関連線維芽細胞; 線維芽細胞

项目成果

The pathophysiological role of oxidized cholesterols in epicardial fat accumulation and cardiac dysfunction: a study in swine fed a high caloric diet with an inhibitor of intestinal cholesterol absorption, ezetimibe.

氧化胆固醇在心外膜脂肪堆积和心脏功能障碍中的病理生理学作用：一项对喂食高热量饮食且含有肠道胆固醇吸收抑制剂依折麦布的猪的研究。

• DOI: 10.1016/j.jnutbio.2016.05.010
• 发表时间: 2016
• 期刊: J Nutr Biochem.
• 作者: Shimabukuro M;Okawa C;Yamada H;Yanagi S;Uematsu E;Sugasawa N;Kurobe H;Hirata Y;Kim-Kaneyama JR;Lei XF;Takao S;Tanaka Y;Fukuda D;Yagi S;Soeki T;Kitagawa T;Masuzaki H;Sato M;Sata M.
• 通讯作者: Sata M.

Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes.

• DOI: 10.1083/jcb.201510036
• 发表时间: 2016-06-06
• 期刊: The Journal of cell biology
• 作者: Petropoulos C;Oddou C;Emadali A;Hiriart-Bryant E;Boyault C;Faurobert E;Vande Pol S;Kim-Kaneyama JR;Kraut A;Coute Y;Block M;Albiges-Rizo C;Destaing O
• 通讯作者: Destaing O

Hic-5 regulates the tumorigenesis of colorectal cancer through stromal remodeling

Hic-5通过基质重塑调节结直肠癌的肿瘤发生

• 发表时间: 2018
• 作者: Petropoulos C;Oddou C;Emadali A;Hiriart-Bryant E;Boyault C;Faurobert E;Vande Pol S;Kim-Kaneyama JR;Kraut A;Coute Y;Block M;Albiges-Rizo C;Destaing O.;Joo-ri Kim-kaneyama
• 通讯作者: Joo-ri Kim-kaneyama

Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.

• DOI: 10.1038/s41598-018-20226-2
• 发表时间: 2018-02-01
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Nozaki M;Haraguchi S;Miyazaki T;Shigeta D;Kano N;Lei XF;Kim-Kaneyama JR;Minakata H;Miyazaki A;Tsutsui K
• 通讯作者: Tsutsui K