Transplanted hair follicle stem cells promoted the recovery of peripheral nerve and spinal cord injuries and have the potential for heart regeneration as well.

移植的毛囊干细胞促进了周围神经和脊髓损伤的恢复，并具有心脏再生的潜力。

• 批准号: 16K10173
• 负责人: Amoh Yasuyuki
• 金额: $ 1.91万
• 依托单位: Kitasato University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K10173/
• 关键词: 毛包幹細胞; ネスチン; 心筋再生; 再生医療; 神経再生; 再生医学

项目成果

Hair follicle associated pluripotent (HAP) stem cell from young mice have the greatest potential to differentiate to cardiac muscle cells

来自年轻小鼠的毛囊相关多能（HAP）干细胞最有可能分化为心肌细胞

• 发表时间: 2016
• 作者: Aiko Yamazaki;Yuko Hamada;Nobuko Arakawa;Masateru Yashiro;Sumiyuki Mii;Ryoichi Aki;Katsumasa Kawahara;Robert M. Hoffman;and Yasuyuki Amoh
• 通讯作者: and Yasuyuki Amoh

Implanted hair-follicle-associated pluripotent (HAP) stem cells encapsulated in polyvinylidene fluoride membrane cylinders promote effective recovery of peripheral nerve injury

• DOI: 10.1080/15384101.2017.1363941
• 发表时间: 2017-01-01
• 期刊: CELL CYCLE
• 影响因子: 4.3
• 作者: Yamazaki, Aiko;Obara, Kohya;Amoh, Yasuyuki
• 通讯作者: Amoh, Yasuyuki

Human hair-follicle associated pluripotent (HAP) stem cells differentiate to neurons, glial cells, keratinocytes, smooth muscle cells, and cardiac muscle cells

人毛囊相关多能 (HAP) 干细胞分化为神经元、神经胶质细胞、角质形成细胞、平滑肌细胞和心肌细胞

• 发表时间: 2016
• 作者: Natsuko Tohgi;Koya Obara;Yuko Hamada;Nobuko Arakawa;Masateru Yashiro;Sumiyuki Mii;Ryoichi Aki;Robert M. Hoffman;and Yasuyuki Amoh
• 通讯作者: and Yasuyuki Amoh

Hypoxia enhances differentiation of hair follicle-associated-pluripotent (HAP) stem cells to cardiac muscle cells

缺氧增强毛囊相关多能（HAP）干细胞向心肌细胞的分化

• DOI: 10.1002/jcb.25734
• 发表时间: 2017
• 期刊: Journal of Cellular Biochemistry
• 影响因子: 4
• 作者: Kyoumi Shirai;Yuko Hamada;Nobuko Arakawa;Aiko Yamazaki;Natsuko Tohgi;Ryoichi Aki, Sumiyuki Mii;Robert M. Hoffman;and Yasuyuki Amoh
• 通讯作者: and Yasuyuki Amoh

Transplantation of nestin-expressing hair spheres rolled in polyvinylidene fluoride membrane (hair sphere roll) promotes the recovery of peripheral nerve injury

移植表达巢蛋白的聚偏二氟乙烯膜卷毛球（毛球卷）促进周围神经损伤的恢复

• 发表时间: 2017
• 作者: Koya Obara;Aiko Yamazaki;Natsuko Tohgi;Kyoumi Shirai;Sumiyuki Mii;Yuko Hamada;Nobuko Arakawa;Ryoichi Aki;Robert M. Hoffman，Yasuyuki Amoh
• 通讯作者: Robert M. Hoffman，Yasuyuki Amoh