Development of a minimally-invasive ECoGmeasurement employing smart metal and MEMS technologies

采用智能金属和 MEMS 技术开发微创 ECoG 测量

• 批准号: 23700493
• 负责人: YAMAKAWA Toshitaka
• 金额: $ 2.75万
• 依托单位: Shizuoka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23700493/
• 关键词: 脳活動記録(レコーディング); 硬膜下電極; 低侵襲; フレキシブル回路技術; ポリイミド; 形状記憶合金; ＭＥＭＳ; 皮質脳波; てんかん

An electrode array which can be implanted with a minimally-invasive procedure and measures ECoG of a wider cortical region than the cranial window with a high spatial resolution have been developed employing MEMS fabrication technology. The safety and capability of the electrodes were confirmed in the phantom experiments which models subdural chronic implantation, and were evaluated with animal tests using monkeys.

采用 MEMS 制造技术开发了一种电极阵列，可以通过微创手术植入，并以高空间分辨率测量比颅窗更宽的皮质区域的 ECoG。电极的安全性和功能在模拟硬膜下慢性植入的体模实验中得到证实，并通过猴子的动物试验进行了评估。

项目成果

Carrier Transportation Properties in M-p-n and Schottky CdTe Diode

M-p-n 和肖特基 CdTe 二极管的载流子传输特性

• 发表时间: 2011
• 作者: Manato Kimura;Akifumi Koike;Takaharu Okunoyama;Hisashi Morii;Shailendra Singh;Toshitaka Yamakawa;Hidenori Mimura;Toru Aoki
• 通讯作者: Toru Aoki

A Low-Cost Long-Life R-R Interval Telemeter with Automatic Gain Control for Various ECG Amplitudes

一种低成本、长寿命的 R-R 间隔遥测仪，具有针对各种心电图幅度的自动增益控制

• 发表时间: 2011
• 作者: Toshitaka Yamakawa;Genki Matsumoto;Toru Aoki
• 通讯作者: Toru Aoki

Minimally-invasive ECoG recording using the novel subdural electrodes manipulated by a shape memory alloy guidewire

使用形状记忆合金导丝操纵的新型硬膜下电极进行微创 ECoG 记录

• 发表时间: 2011
• 作者: Toshitaka Yamakawa;Takeshi Yamakawa;Takao Inoue;Shuji Aou;Satoru Ishizuka;Masami Fujii;Michiyasu Suzuki
• 通讯作者: Michiyasu Suzuki

Development of a Focal Brain Cooling Device for the Treatment of Intractable Epilepsy

开发用于治疗顽固性癫痫的局部脑冷却装置

• 发表时间: 2012
• 作者: Toshitaka Yamakawa;Takeshi Yamakawa;Takao Inoue;Tatsuji Tokiwa;Shuji Aou;Toru Aoki;Yuichi Maruta;Masami Fujii;Michiyasu Suzuki
• 通讯作者: Michiyasu Suzuki

Cooling of the epileptic focus suppresses seizures with minimal influence on neurologic functions

• DOI: 10.1111/j.1528-1167.2011.03388.x
• 发表时间: 2012-03-01
• 期刊: EPILEPSIA
• 影响因子: 5.6
• 作者: Fujii, Masami;Inoue, Takao;Suzuki, Michiyasu
• 通讯作者: Suzuki, Michiyasu