Visualization of circadian rhythm in suprachiasmatic nucleus usinggreen fluorescent protein transgenic rats

使用绿色荧光蛋白转基因大鼠观察视交叉上核昼夜节律

• 批准号: 23790280
• 负责人: FUJIHARA Hiroaki
• 金额: $ 2.66万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23790280/
• 关键词: eGFP; 視交叉上核; バゾプレッシン; サーカディアンリズム; 視交叉娘核

I examined the effect of LED light stimulus to the suprachiasmatic nucleus (SCN) and the paraventricular nucleus (PVN) in mouse. The Fos-ir cells were increased in the SCN and the PVN after blue LED light stimulus. I investigated the gene expression in jet lag model using arginine vasopressin (AVP)-eGFP transgenic rats. The Per3gene is increased in the SCN in the jet lag AVP-eGFP transgenic rats.

我检查了 LED 光刺激对小鼠视交叉上核 (SCN) 和室旁核 (PVN) 的影响。蓝光 LED 光刺激后，SCN 和 PVN 中的 Fos-ir 细胞增加。我使用精氨酸加压素 (AVP)-eGFP 转基因大鼠研究了时差模型中的基因表达。时差AVP-eGFP转基因大鼠的SCN中Per3基因增加。

项目成果

Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus

血管紧张素 II 1 型受体信号通过下丘脑中抑制食欲的促肾上腺皮质激素释放激素调节进食行为

• DOI: 10.1074/jbc.m110.192260
• 发表时间: 2011
• 期刊: Journal of Biological Chemistry
• 影响因子: 4.8
• 作者: Yamamoto;R. Akazawa;H. Fujihara;H. Ozasa;Y. Yasuda;N. Ito;K. Kudo;Y. Qin;Y. Ueta;Y. & Komuro;I
• 通讯作者: I

Water deprivation induces appetite and alters metabolic strategy in Notomys alexis: unique mechanisms for water production in the desert

• DOI: 10.1098/rspb.2011.2627
• 发表时间: 2012-07-07
• 期刊: PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
• 影响因子: 4.7
• 作者: Takei, Yoshio;Bartolo, Ray C.;Donald, John A.
• 通讯作者: Donald, John A.

Upregulation of arginine vasopressin synthesis in the rat hypothalamus after kainic acid-induced seizures

• DOI: 10.1016/j.brainres.2011.09.030
• 发表时间: 2011-11-18
• 期刊: BRAIN RESEARCH
• 影响因子: 2.9
• 作者: Iwanaga, Masaru;Ohno, Motoko;Ueta, Yoichi
• 通讯作者: Ueta, Yoichi

Highly Visible Expression of an Oxytocin-Monomeric Red Fluorescent Protein 1 Fusion Gene in the Hypothalamus and Posterior Pituitary of Transgenic Rats

• DOI: 10.1210/en.2011-0006
• 发表时间: 2011-07-01
• 期刊: ENDOCRINOLOGY
• 影响因子: 4.8
• 作者: Katoh, Akiko;Fujihara, Hiroaki;Ueta, Yoichi
• 通讯作者: Ueta, Yoichi

Possible contribution of pannexin channel to ATP-induced currents in vitro in vasopressin neurons isolated from the rat supraoptic nucleus

• DOI: 10.1016/j.brainres.2011.04.017
• 发表时间: 2011-06-07
• 期刊: BRAIN RESEARCH
• 影响因子: 2.9
• 作者: Ohbuchi, Toyoaki;Yokoyama, Toru;Ueta, Yoichi
• 通讯作者: Ueta, Yoichi