Comprehensive analysis of functional monomer in dental adhesives using molecular-level analysis technique and investigation of the most suitable composition of adhesives

利用分子水平分析技术全面分析牙科粘合剂中的功能单体并研究最合适的粘合剂成分

• 批准号: 23592798
• 负责人: TORII Yasuhiro
• 金额: $ 3.24万
• 依托单位: Okayama University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592798/
• 关键词: 接着; 機能性モノマー; 歯質; エックス線回折; 微細構造解析; 歯質接着材; 10-MDP; エックス線解析; プライマーアドヘーシブ; 重合触媒; 活性ラジカル; エックス線回折(XRD); エネルギー分散型Ｘ線分析(EDS); 透過型電子顕微鏡(TEM/STEM); 層状構造; 接着; 機能性モノマー; 歯質; エックス線回折; 微細構造解析; 歯質接着材; 10-MDP; エックス線解析; プライマーアドヘーシブ; 重合触媒; 活性ラジカル; エックス線回折(XRD); エネルギー分散型Ｘ線分析(EDS); 透過型電子顕微鏡(TEM/STEM); 層状構造

It was reported that 10-MDP promoted formation of self-assembled layering at resin- hydroxyapatite interface when it was applied. Firstly, this study showed that the commercial 10-MDP based adhesives also formed the self-assembled layering of two 10-MDP molecules, joined by stable MDP-Ca salt formation, at the interface between human dentin and resin as similar to 10-MDP solution. The three-dimensional observation with FIB-SEM revealed that MDP-Ca salt was formed at the interface, extending into the adhesive (resin) layer. When we prepared adhesives containing MDP-Ca salts as a model of adhesion layer and measured its properties, polymerization shrinkage decreased and some of properties increased by adding the salt. It is concluded that MDP-containing adhesives do form nano-layering at the adhesive interface and MDP-Ca salt spread through the adhesive layer. The properties of adhesive layer with resin, salts and other residual tooth substances may influence the adhesion.

据报道，应用于树脂羟基磷灰石界面时促进了自组装分层的形成。 首先，这项研究表明，基于10-MDP的商业粘合剂还形成了两个10-MDP分子的自组装分层，在人牙本质和树脂之间的界面与10-MDP溶液相似，并在稳定的MDP-CA盐形成上加入。使用FIB-SEM的三维观察结果表明，MDP-CA盐在界面形成，延伸到粘合剂（树脂）层。 当我们制备含有MDP-CA盐作为粘附层模型并测量其性质的粘合剂时，聚合收缩量减少，而某些特性通过添加盐来增加。得出的结论是，含MDP的粘合剂确实在粘合剂界面形成纳米层，而MDP-CA盐通过粘合剂层扩散。带有树脂，盐和其他残留牙齿物质的粘合剂层的特性可能会影响粘附。