Identification of the expression mechanism of the virulence factors by quorum sensing in plant pathogen and its application

植物病原菌毒力因子表达机制的群体感应鉴定及其应用

• 批准号: 21780063
• 负责人: MOROHOSHI Tomohiro
• 金额: $ 2.91万
• 依托单位: Utsunomiya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21780063/
• 关键词: クオラムセンシング; アシル化ホモセリンラクトン; 植物病原菌; Pantoea ananatis; quorum sensing; acylhomoserine lactone; plant pathogen; 転写制御; 菌体凝集; アドヘシン; 菌体外多糖; 病原性因子

Many plant pathogens have a quorum-sensing system, a cell-cell communication mechanism that depends on cell population density. Several kinds of N-acyl homoserine lactone (AHL) have been identified as signal compounds involved in this mechanism. In this study, we attempted to identify the unknown factors, which were regulated by AHL-mediated quorum sensing in the plant pathogen Pantoea ananatis SK-1. As the results, it was revealed that the production of extracellular polysaccharide (EPS) and cell aggregation were regulated by AHL-mediated quorum sensing in P. ananatis SK-1.

许多植物病原体具有群体感应系统，这是一种取决于细胞群体密度的细胞间通讯机制。几种 N-酰基高丝氨酸内酯 (AHL) 已被确定为参与该机制的信号化合物。在本研究中，我们试图鉴定植物病原体 Pantoea ananatis SK-1 中受 AHL 介导的群体感应调节的未知因子。结果表明，P. ananatis SK-1 中胞外多糖 (EPS) 的产生和细胞聚集受到 AHL 介导的群体感应的调节。

项目成果

Pantoea ananatisのQuorum Sensingに制御される病原性因子の探索

寻找菠萝泛菌中群体感应控制的毒力因子

• 发表时间: 2012
• 作者: 藤井智久;他3名;諸星知広,菊池健太,緒方優二,上岡夏海,池田宰
• 通讯作者: 諸星知広,菊池健太,緒方優二,上岡夏海,池田宰

植物病原菌Pantoea ananatisのクオラムセンシングによる菌体外多糖生産制御機構の解析

植物病原真菌菠萝泛菌群体感应控制胞外多糖产生机制分析

• 发表时间: 2009
• 作者: 齋藤政則;篠山浩文;齋藤明広;知久和寛;安藤昭一;大関貴恵美,諸星知広,池田宰
• 通讯作者: 大関貴恵美,諸星知広,池田宰

Cell aggregation is negatively regulated by N-acylhomoserine lactone-mediated quorumsensing in Pantoea ananatis SK-1

Pantoea ananatis SK-1 中 N-酰基高丝氨酸内酯介导的群体感应对细胞聚集产生负调控

• DOI: 10.1016/j.jbiosc.2011.08.004
• 发表时间: 2011
• 期刊: J.Biosci.Bioeng.
• 作者: T.Morohoshi;Y.Ogata;T.Ikeda
• 通讯作者: T.Ikeda

Exopolysaccharide Production Is Influenced by Sugars, N-Acylhomoserine Lactone, and Transcriptional Regulators RcsA and RcsB, but Does Not Affect Pathogenicity in the Plant Pathogen Pantoea ananatis

胞外多糖的产生受糖、N-酰基高丝氨酸内酯以及转录调节因子 RcsA 和 RcsB 的影响，但不影响植物病原体 Pantoea ananatis 的致病性

• DOI: 10.1271/bbb.100888
• 发表时间: 2011
• 期刊: Bioscience, Biotechnology, and Biochemistry
• 作者: T.Morohoshi;K.Oseki;T.Ikeda
• 通讯作者: T.Ikeda

Cell aggregation is regulated by N-acylhomoserine lactone-mediated quorum sensing in the plant pathogen Pantoea ananatis

植物病原体 Pantoea ananatis 中的细胞聚集受 N-酰基高丝氨酸内酯介导的群体感应调节

• 发表时间: 2011
• 作者: T.Morohoshi;Y.Ogata;T.Ikeda
• 通讯作者: T.Ikeda