Analysis of visual fixation patterns among infants--a potential index for early intervention for children with pervasive developmental disorders--

婴儿视固视模式分析——广泛性发育障碍儿童早期干预的潜在指标——

• 批准号: 21730546
• 负责人: INOUYE Jun
• 金额: $ 2.75万
• 依托单位: Hamamatsu University School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21730546/
• 关键词: 疫学; メンタルヘルス; 在日外国人; 子ども; 広汎性発達障害; 注視点の異常; 広汎性発逹障害

Social and behavioural outcomes of children with pervasive developmental disorders (PDD) depend upon timing she/he receives clinical intervention ; the earlier intervention measures are initiated, the better the outcome is. Thus, early diagnosis of PDD is a crucial key to start the intervention and to improve prognosis. Recently, studies have suggested that visual fixation patterns of children with PDD differ significantly from those of typically developing children at as early as 1 or 2 years of age. If one can successfully detect the abnormalities in the visual fixation patterns among those with potential diagnosis of PDD, the children and the family do not have to wait for firm diagnosis made at around the age of 3 years by an expert clinicians, who make the diagnosis on the basis of their subjective judgments. In this study, we planned to employ a novel device with which visual fixation pattern is easily detected without any fixation of head movement, to detect investigate diagnosi … More s as early as 2 years, without any expertise of clinicians.We enrolled typically developing children (N=17, 2 to 12 years) and children with a clinical diagnosis of PDD (N=20, 3 to 10 years). With the device called "eye-tracker", which Professor Yoshinobu Ebisawa (Shizuoka University, Department of System Technology) invented, we measured the timing and duration of visual fixation of children of the both groups, and analysed proportion of duration in which each individual gazed on the target areas, such as "eye area", "mouth area", and "other area".The results showed that children with PDD had shorter duration of gazing on "eye area" than did typically developing children. As for diagnosis of PDD, an index of [duration on eye area] divided by [duration on mouth area] was proposed, and, if the index is smaller than 0.7, the children were successfully judged to have a diagnosis of PDD, with a positive predictive value of 70%.With our novel device, we successfully detected an aberrant visual fixation pattern in children with PDD, and found that the early diagnosis of PDD can be drawn without any expertise. Less

患有普遍发育障碍（PDD）儿童的社会和行为结果取决于她/他接受临床干预的时间；开始了较早的干预措施，结果越好。这是PDD的早期诊断是开始干预并改善预后的关键关键。最近，研究表明，患有PDD儿童的视觉固定模式与最早在1或2岁时的典型患者不同。如果一个人能够成功地检测到具有PDD诊断诊断的人的视觉固定模式异常，那么儿童和家庭就不必等待专家临床医生在3岁左右进行的固件诊断，这些临床医生是根据主观法官进行诊断的。在这项研究中，我们计划采用一种新颖的设备，可以轻松检测到视觉固定模式，而无需进行任何头部运动的任何固定，以检测研究诊断，最早2岁，而没有任何临床医生的专业知识。我们招募了典型的儿童（n = 17、2至12岁）和患有PDD临床诊断的儿童（n = 20，3至10年）。凭借该设备称为“眼线笔”，该设备被发明了Yoshinobu Ebisawa（Shizuoka University，System Technology系），我们衡量了两组儿童的视觉固定的时间和视觉固定的时间和持续时间，并分析了持续时间的比例，每个人都注视着目标区域，例如“眼睛区域”，例如“眼睛区域”，“嘴巴”，“嘴巴”和其他地区的居民和其他盖帽”和其他盖帽。在“眼睛区域”上，比通常成长的儿童。至于诊断PDD，提出了[眼睛区域持续时间]除以[口径持续时间]的指数，如果指数小于0.7，则成功判断儿童的PDD诊断为PDD，为阳性预测值为70％。借助我们的新设备，我们成功地检测到了PDD儿童的异常视觉固定模式，并发现可以在没有任何专业知识的情况下绘制PDD的早期诊断。较少的