Microwave-assisted rapid fabrication of high performance monolithic capillary column

微波辅助快速制造高性能整体式毛细管柱

• 批准号: 20750058
• 负责人: LIM Leewah
• 金额: $ 2.91万
• 依托单位: Gifu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20750058/
• 关键词: モノリス型キャピラリーカラム; マイクロ波; 迅速調製; 液体クロマトグラフィー; キャピラリーLC; モノリスカラム; 迅速調製法; 高性能化

Rapid fabrication of monolithic silica- and polymer-based capillary columns were evaluated using microwave irradiation. The reaction solution was filled into fused-silica capillary tubing and the column was then irradiated at different time under various temperature and output control of the microwave device. The morphology of the monoliths was also observed with a scanning electron microscope (SEM) and was compared to those monoliths that were fabricated under conventional conditions. As the results, as for the silica-based monolith, high performance capillary column was obtained when the column was irradiated at output 300 W for 1 h during the sol-gel reaction, which was normally carried out for 24 h. As for the polymer-based monolith, radiation output at 200W for 15 min was enough to make a relatively high performance capillary column for normal liquid chromatographic separation.

使用微波辐射评估了基于整体二氧化硅和聚合物的毛细管柱的快速制造。将反应溶液填充到熔融石英毛细管中，然后在微波装置的不同温度和输出控制下在不同时间照射柱。还使用扫描电子显微镜（SEM）观察了整料的形态，并将其与在常规条件下制造的那些整料进行了比较。结果，对于基于二氧化硅的整体柱，当在溶胶-凝胶反应期间以300W的输出功率照射柱1小时时，获得高性能毛细管柱，该反应通常进行24小时。对于基于聚合物的整体材料，200W的辐射输出15分钟足以制成用于正常液相色谱分离的相对高性能的毛细管柱。

项目成果

マイクロ波を利用した高性能モノリス型キャピラリーカラムの迅速調製法の確立

高性能整体毛细管柱微波快速制备方法的建立

• 发表时间: 2009
• 作者: 河野恵子;滝口裕実;桑島修一郎;岩田博夫;小寺秀俊;和佐清孝;秦猛志・占部弘和;リムリーワ・玉田真人・石原真裕・竹内豊英
• 通讯作者: リムリーワ・玉田真人・石原真裕・竹内豊英

マイクロウェーブを用いたモノリス型シリカキャピラリーカラムの迅速調製に関する研究

微波快速制备整体式硅胶毛细管柱的研究

• 发表时间: 2008
• 作者: Kenichiro Todoroki;Hidemichi Etoh;Hideyuki Yoshida;Hitoshi Nohta;Masatoshi Yamaguchi;玉田真人・リムリーワ・竹内豊英
• 通讯作者: 玉田真人・リムリーワ・竹内豊英