The next generation structural biology using a new pulsed-neutron diffractometer
使用新型脉冲中子衍射仪的下一代结构生物学
基本信息
- 批准号:20612002
- 负责人:
- 金额:$ 2.75万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2008
- 资助国家:日本
- 起止时间:2008 至 2010
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
A new diffractometer for protein crystallography (iBIX) at the next generation pulsed-neutron source at J-PARC, has been completed and operational since the end of 2008. After various commissionings, data collection of ribonuclease A could be done at the accelerator power of 120kW for a crystal of 5 mm3 in volume for about 10 days as the first protein sample at iBIX. As a result of structural analysis, hydrogen position and orientation of waters for a purpose could be confirmed. According to the result, it turned out that it is possible to collect a full data set of a protein in about 3 days for a crystal of 1 mm3 in volume when J-PARC accelerator power becomes 1MW and 30 detectors of iBIX are provided as a total as scheduled.
自2008年底以来,J-PARC的下一代脉冲 - 中子源蛋白质晶体学(IBIX)的新衍射仪已完成和运行。在各种委员会之后,核糖核酸酶的数据收集可以在120kW的加速剂功率上完成,该加速器功率为120kW的含量为120kW,用于5 mm3的晶体,用于大约10天的crystal pers prient of 10天,以供您使用10天的primits protein protein protein protein protein protein protein proteine protherein protherein protherein protect in ib。由于结构分析,可以证实有目的的水的氢位置和水的方向。根据结果,事实证明,当J-Parc加速器功率变为1MW时,可以在大约3天内收集蛋白质的完整数据集,并总共提供30个IBIX探测器,并按计划总共提供。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Large single crystal growth and preliminary neutron diffraction analysis of Achromobacter protease I
无色杆菌蛋白酶 I 的大单晶生长和初步中子衍射分析
- DOI:
- 发表时间:2008
- 期刊:
- 影响因子:0
- 作者:Y. Ohnishi;I. Tanaka;N. Niimura;et.al.
- 通讯作者:et.al.
A neutron crystallographic analysis of a cubic porcine insulin at pD6.6
pD6.6 立方猪胰岛素的中子晶体分析
- DOI:
- 发表时间:2008
- 期刊:
- 影响因子:0
- 作者:Takuya Ishikawa;Ichiro Tanaka;他
- 通讯作者:他
Abnormal pKa value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis
中子晶体分析揭示胰岛素分子内部组氨酸pKa值异常
- DOI:
- 发表时间:2008
- 期刊:
- 影响因子:0
- 作者:Takuya Ishikawa;Ichiro Tanaka;et.al.
- 通讯作者:et.al.
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
TANAKA Ichiro其他文献
TANAKA Ichiro的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('TANAKA Ichiro', 18)}}的其他基金
Development of a diagnosis and treatment support system for facial movement disorders by three-dimensional dynamic facial expression analysis of video images
基于视频图像三维动态面部表情分析开发面部运动障碍诊疗支持系统
- 批准号:
17K11553 - 财政年份:2017
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of the system to assist diagnosis, treatment and surgical planning for disorder of facial movement utilizing computerized analysis of facial expression based on video images
开发利用基于视频图像的面部表情计算机分析来辅助面部运动障碍的诊断、治疗和手术计划的系统
- 批准号:
23592657 - 财政年份:2011
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Application of surface modified colloidal nano-dots for organic memory transistors
表面改性胶体纳米点在有机存储晶体管中的应用
- 批准号:
23510132 - 财政年份:2011
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Epigenetics during pollination and fertilization in higher plants
高等植物授粉和受精过程中的表观遗传学
- 批准号:
22570068 - 财政年份:2010
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of an assisting system for diagnosis, treatment and surgical planning of disorder of facial movement utilizing computerized three dimensional analysis of facial expression based on video images
利用基于视频图像的计算机三维面部表情分析开发面部运动障碍的诊断、治疗和手术计划辅助系统
- 批准号:
20592108 - 财政年份:2008
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Mechanisms underlying the effect of immunotherapy for anti-factor VIII inhibitor antibodies
抗因子 VIII 抑制剂抗体免疫治疗作用的机制
- 批准号:
20591258 - 财政年份:2008
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Thin filmtransistors using 2-dimensional crystals of colloidal dots
使用胶体点二维晶体的薄膜晶体管
- 批准号:
20510105 - 财政年份:2008
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Expression of factor VIII activity in the presertce of anti-factor VIII inhibitor antibodies
存在抗因子 VIII 抑制剂抗体时因子 VIII 活性的表达
- 批准号:
18591198 - 财政年份:2006
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Analysis of molecular basis between heterochromatin and euchromatin in plant cells
植物细胞异染色质和常染色质的分子基础分析
- 批准号:
18570061 - 财政年份:2006
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of a diagnostic and therapeutic supporting system for disorder of facial movement based on video- image analysis of facial expression
基于面部表情视频图像分析的面部运动障碍诊断和治疗支持系统的开发
- 批准号:
17591877 - 财政年份:2005
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)