Development of an oral appliance that induces mandibular protrusion only when sleep apnea occurs and that positive pressure is driven if the apnea disappears

开发一种口腔矫治器，仅在发生睡眠呼吸暂停时引起下颌前突，并且在呼吸暂停消失时驱动正压

• 批准号: 19592292
• 负责人: YOSHIDA Kazuya
• 金额: $ 2.91万
• 依托单位: Department of Clinical Research, National Hospital Organization Kyoto Medical Center
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19592292/
• 关键词: 睡眠時無呼吸症候群; 口腔内装置; CPAP; 経鼻持続陽圧呼吸療法; 下顎運動; 持続陽圧呼吸療法; 神経生理学

We tried to develop an oral appliance that induces mandibular protrusion only when sleep apnea occurs and that positive pressure is driven if the apnea disappears. We attempted to change a soft program of continuous positive airway pressure but during the study period did not make it. The research is necessary further investigation.The somatosensory evoked magnetic field analysis of electrical stimulation of the tongue was found to be useful to get information about finding and developing a sense of tongue and sleep apnea syndrome.Measuring cerebral blood flow using near-infrared spectroscopy in patients with sleep apnea syndrome, dysfunction of the frontal lobe was elucidated with the syndrome.

我们试图开发一种只有在睡眠呼吸暂停时才引起下颌骨的口服设备，如果呼吸暂停消失，则驱动正压。我们试图改变一个连续气道压力的软程序，但在研究期间没有这样做。这项研究是必要的进一步研究。发现舌头电刺激的磁场诱发磁场分析被发现有用，可用于获取有关舌和睡眠呼吸暂停综合征的信息。使用近红外光谱症状的脑血流来衡量睡眠呼吸暂停综合症患者的近红外光谱，并与Frontal lobe的功能不合时宜。