Study of dynamic contrast-enhanced MRI in the maxillofacial region

颌面部动态增强MRI研究

• 批准号: 19592170
• 负责人: ASAUMI Junichi
• 金额: $ 2.83万
• 依托单位: Okayama University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19592170/
• 关键词: ダイナミックMRI; 口腔扁平上皮癌; contrast index; PCNA; microvessel density; 腫瘍血管新生; 腫瘍増殖能; Contrast Index; MIB-1(Ki-67); CD44; CD133; VEGF; Flk-1; MRI; 唾液腺腫瘍; 良性; 悪性

The histopathological prognostic factors, tumor proliferation and microvessel density (MVD) showed significant correlations with enhancement parameters in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in oral squamous cell carcinoma (SCC). The assessment of DCE-MRI parameters may prove to be a valuable non-invasive method for assessing tumor cell proliferation and MVD of patients with oral cancer.

组织病理学预后因素，肿瘤增殖和微血管密度（MVD）显示出与口腔鳞状细胞癌（SCC）中动态对比增强磁共振成像（DCE-MRI）中增强参数的显着相关性。 DCE-MRI参数的评估可能被证明是评估口腔癌患者肿瘤细胞增殖和MVD的有价值的非侵入性方法。

项目成果

Dynamic contrast-enhanced magnetic resonance imaging for estimating tumor proliferation and microvessel density of oral squamous cell carcinomas

• DOI: 10.1016/j.oraloncology.2008.09.003
• 发表时间: 2009-07-01
• 期刊: ORAL ONCOLOGY
• 影响因子: 4.8
• 作者: Unetsubo, Teruhisa;Konouchi, Hironobu;Asaumi, Jun-ichi
• 通讯作者: Asaumi, Jun-ichi

A new phantom using polyethylene glycol as an apparent diffusion coefficient standard for MR imaging

• DOI: 10.3892/ijo_00000404
• 发表时间: 2009-10-01
• 期刊: INTERNATIONAL JOURNAL OF ONCOLOGY
• 影响因子: 5.2
• 作者: Matsuya, Ryohei;Kuroda, Masahiro;Inamura, Keiji
• 通讯作者: Inamura, Keiji