Augmentation of an immunomodulating activities of functional polysaccharides by an interactive effect with food factors

通过与食物因子的相互作用增强功能性多糖的免疫调节活性

• 批准号: 19700577
• 负责人: MINATO Ken-ichiro
• 金额: $ 2.39万
• 依托单位: Miyagi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19700577/
• 关键词: 調理と機能性成分; 機能性糖鎖; 免疫調節機能; 成分間相互作用; 食用キノコ; ナメコ; タモギタケ; 多糖; マクロファージ; M1マクロファージ; 免疫調節作用; 加熱調理; 食品; 糖; ビタミンD2; 核酸; サイトカイン; Th1

It was shown that an immunomodulating activity of functional polysaccharides from edible mushrooms was regulated by some kinds of food factors, such as guanylic acid and vitamin D2, through their interaction. However, it was suggested that their immunomodulating activities were not changed by a differentiation of processing. This work suggested that functional polysaccharides were effective on prevention from disease in our life because of maintenance of their immunomodulating activities.

研究表明，食用菌功能性多糖的免疫调节活性是通过鸟苷酸和维生素 D2 等食物因子的相互作用来调节的。然而，有人认为它们的免疫调节活性不会因加工的差异而改变。这项工作表明，功能性多糖由于其免疫调节活性的维持，可以有效预防我们生活中的疾病。

项目成果

An immunomodulating action of a polysaccharide fraction from an ed ible mushroom, Pleurotus cornucopiae var. citrinopileatus

来自食用蘑菇 Pleurotus cornucopiae var. 的多糖组分的免疫调节作用。

• 发表时间: 2008
• 期刊: J. Clin. Biochem. Nutr 43
• 作者: Minato K.;and Abe C
• 通讯作者: and Abe C

An immunomodulating action of a polysaccharide fraction from an edible mushroom, Pleurotus cornucopiae var.citrinopileatus

食用菌 Pleurotus cornucopiae var.citrinopileatus 多糖组分的免疫调节作用

• 期刊: J.Clin, Biochem.Nutr (in press)
• 作者: Minato K.;and Abe C;Minato K.;Minato K. and Abe C.
• 通讯作者: Minato K. and Abe C.

A polysaccharide fraction from an edible mushroom, Pleurotus cornucopiae var. citrinopileatus stimulates an immunomodulating action of murine macrophage, RAW264, on TNF-a and NO productions in vitro

来自食用菌 Pleurotus cornucopiae var. 的多糖组分。

• 发表时间: 2009
• 期刊: Int. J. Medicin. Mushrooms 10 (3)
• 作者: 柴田克己;廣瀬潤子(渡辺明治;福井富穂編);湊健一郎;Minato K
• 通讯作者: Minato K

ナメコ中機能性多糖のサイトカイン産生作用の検討

滑子培养基功能性多糖的细胞因子产生效果的考察

• 发表时间: 2010
• 作者: 湊健一郎;阿部千鶴;櫻井香子;田川裕士;鈴木勇治;タモギタケ
• 通讯作者: タモギタケ

A polysaccharide fraction from an edible mushroom, Pleurotus cornucopiae var. citrinopileatus stimulates an immunomodulating action of murine macrophage, RAW264, on TNF-αand NO productions in vitro.

来自食用蘑菇 Pleurotus cornucopiae var. 的多糖组分可在体外刺激小鼠巨噬细胞 RAW264 对 TNF-α 和 NO 产生的免疫调节作用。

• 发表时间: 2008
• 期刊: Int. J. Medicin. Mushrooms 10(3)
• 作者: 柴田克己;廣瀬潤子(渡辺明治;福井富穂編);湊健一郎;Minato K;Minato K.
• 通讯作者: Minato K.