Attempt to find the threshold of incremental cost-effectiveness ratio for a new drug to accept it in national health insurance

尝试寻找新药纳入全民医保的增量成本效益比阈值

• 批准号: 19590521
• 负责人: SHIRAGAMI Makoto
• 金额: $ 2.91万
• 依托单位: Nihon University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19590521/
• 关键词: 増分費用効果比; 薬価; 治療充足度; 医療保険; 新医薬品; 効用値

Considering the notion, prevailing in western countries, that the pharmaceutical should not be reimbursed by health insurance unless its Incremental Cost-effectiveness Ratio (ICER) is less than some pre-decided value, we tried to find the pre-decided value suitable to Japanese system based on the prices of 73 new products in Japan. ICER varied widely from 1200000 yen to 19000000 yen. This indicates that the current rule for calculating pharmaceuticals' price dose not necessarily reflect cost-effectiveness of new pharmaceutical. Reverse correlation was found between ICER for a disease and medical satisfaction. It suggests that ICERs for diseases classified by medical satisfaction can be used as pre-decided values under current price calculating system.

考虑到西方国家普遍存在的概念，除非其渐进的成本效益比（ICER）少于某些预先决定的价值，否则不应通过健康保险来偿还药品，我们试图根据日本73种新产品的价格找到适合日本系统的预先决定的价值。 ICER从1200000日元到19000000日元。这表明计算药品价格剂量的当前规则不一定反映新药的成本效益。在ICER之间发现了疾病和医疗满意度之间的反向相关性。它表明，在当前价格计算系统下，可以用医学满意度分类的疾病ICER作为预先决定的值。

项目成果

急性心不全におけるカルペリチド治療の臨床的有用性と医療経済性

卡培肽治疗急性心力衰竭的临床效用和医疗经济学

• 发表时间: 2007
• 期刊: 呼吸と循環 55,7
• 作者: 船崎俊一;白神誠;詫間浩樹
• 通讯作者: 詫間浩樹

Cost-effectiveness of salmeterol/fluticasone combination therapy vs fluticasone propionate in Japanese asthmatic patients

沙美特罗/氟替卡松联合治疗与丙酸氟替卡松治疗日本哮喘患者的成本效益

• 发表时间: 2010
• 期刊: Yakugaku Zasshi 130(4)
• 作者: Yuji Tohda;Sankei Nishima;Ichiro Arakawa;Makoto Shiragami;Terumasa Miyamoto
• 通讯作者: Terumasa Miyamoto

Cost-effectiveness of Salmeterol/Fluticasone Combination Therapy vs. Fluticasone Propionate in Japanese Asthmatic Patients

沙美特罗/氟替卡松联合疗法与丙酸氟替卡松在日本哮喘患者中的成本效益

• 发表时间: 2010
• 期刊: YAKUGAKU ZASSHI 130(4)
• 作者: Yuji Tohda;Sankei Nishima;Ichiro Arakawa;Makoto Shiragami;Terumasa Miyamoto
• 通讯作者: Terumasa Miyamoto

Pharmacoeconomic Analysis of Hypertriglyceridemia Treatment at the Medical Institutions

医疗机构治疗高甘油三酯血症的药物经济学分析

• 发表时间: 2008
• 期刊: YAKUGAKU ZASSHI 128(12)
• 作者: T. Takahashi;Y. Saegusa;Y. Takimoto;M. Shiragami
• 通讯作者: M. Shiragami