Intensive training for unilateral spatial neglect with repetitive transcranial magnetic stimulation

通过重复经颅磁刺激进行单侧空间忽视的强化训练

• 批准号: 18500412
• 负责人: OGATA Atsuko
• 金额: $ 2.03万
• 依托单位: Kagoshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18500412/
• 关键词: unilateral spatial neglect; transcranial magnetic stimulation; reaching task; stroke; BIT; 集中的訓練; 訓練効果; リハビリテーション

The aim of the study was to investigate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected hemisphere and a computerized reaching task can ameliorate visuospatial neglect in stroke patients.The subjects were 3 patients with left unilateral spatial neglect (USN) with stroke. Neurological examination showed contralateral hemiparesis and contralateral visuospatial neglect assessed by Behavioural Inattention Test (BIT) and a computerized simple and delayed reaction time. The experimental schedule consisted of rTMS and reaching task sessions delivered 10 days for two consecutive weeks. Each session consisted of one train of 300 pulses delivered at 90% of motor threshold by means of a focal eight-shaped coil placed over P5 (according to the EEG 10/20 system) and simple and delayed computerized reaching task (20-30 min). Patients tolerated rTMS treatment well and no adverse events were reported.rTMS and reaching task induced an improvement of visuospatial performance. Our data need to be confirmed in larger series by controlled studies.

该研究的目的是研究在未受影响的半球上低频重复的经颅磁刺激（RTMS）以及计算机化的任务是否可以改善中风患者的视觉空间忽视。受试者是3例患有STROKE的左单层空间疏忽（USN）的患者。神经系统检查显示，通过行为不集中测试（BIT）评估的对侧偏瘫和对侧视觉空间忽视和计算机化的简单和延迟的反应时间。实验时间表包括RTM和执行任务课程连续两周进行的10天。每个课程由一列300张脉冲的火车组成，该脉冲通过放置在P5上的焦点八形线圈（根据EEG 10/20系统）以及简单而延迟的计算机触时任务（20-30分钟）。患者对RTMS治疗的耐受性很好，没有报告不良事件。RTMS和达到任务引起的视觉空间性能的改善。我们的数据需要通过对照研究在较大的系列中确认。

项目成果

左半側空間無視に対する連続的経頭蓋磁気刺激とりーチング課題を併用した集中的訓練の効果

强化训练联合持续经颅磁刺激及教学任务对左半侧空间忽视的影响

• 发表时间: 2008
• 作者: 衛藤誠二;緒方敦子;下堂薗恵;川平和美;鎌田克也;砂永彩子
• 通讯作者: 砂永彩子

Effect of intensive training for unilateral spatial neglect with repetitive transcranial magnetic stimulation and reaching task

重复经颅磁刺激和伸手任务强化训练对单侧空间忽视的效果

• 发表时间: 2008
• 作者: seiji Etoh;Atsuko Ogata;Megumi Shimodozono;Kazum Kawahira;Katsuya Kamata;Ayako Sunanaga
• 通讯作者: Ayako Sunanaga