Longitudinal study of the benefit of exercise training for the prevention of age-related decline in activity of daily living and cognitive function

运动训练对预防与年龄相关的日常生活活动能力和认知功能下降的益处的纵向研究

基本信息

批准号：
16300224
负责人：
TOBA Kenji
金额：
$ 8.58万
依托单位：
Kyorin University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2006
项目状态：
已结题

项目摘要

This research was conducted to find a suitable exercise training program to prevent age-related functional decline in older adults. The cohort is members of athletic sports club branched all over Japan : 4,700 people, 16-88 years old (average age 54.8 y/o). We followed physical fitness, independence of ADL, cognitive function, depressive mood, participation in social activities and others. After three years of follow-up period, we obtained following findings. (1) Vitality scale (VS) provides a reliable and valid measure for the QOL of the healthy elderly individuals, and exercise appears beneficial for preventing age-associated decline in VS. (2) Regular exercise for a long period prevents age-associated decline in VS, thereby contributing to care prevention for elderly individuals. (3) Regular exercise in climacteric women gives various benefits, such as decrease in body fat, increase in bone mass, prevention of arteriosclerosis, and balance capability. (4) Appropriate exercise can improve multiple (physical, metabolic, and psychological) functions of healthy elderly individuals. (5) For elderly people who do exercise regularly, past history of fall, tripping, and age are the independent predictors of future falls. 【○!6】 From an animal study, regular exercise prevents atherosclerosis by augmenting antioxidant capacity.Our studies established a useful measure to evaluate the QOL of healthy middle-life and elderly individuals. The vitality scale will give benefit to identify frail people who will possibly enter into care-need status. With this scale, exercise was shown to prevent age-related decline in VS. We were also able to demonstrate various benefits exercise can give, such as anti-arteriosclerotic effect and increase in bone mass. We are still pursuing this cohort, and hope to keep obtaining important data about the effect of exercise.

进行了这项研究是为了找到合适的运动训练计划，以防止老年人与年龄相关的功能下降。该队列是在日本各地分支机构的体育俱乐部的成员：4,700人，16-88岁（平均年龄为54.8 y/o）。我们遵循身体健康，ADL的独立性，认知功能，抑郁情绪，参与社交活动等。经过三年的随访期，我们获得了以下发现。（1）活力量表（VS）为健康的老年人提供了可靠且有效的测量，运动似乎有益于防止与年龄相关的VS下降。（2）长期定期锻炼可防止与年龄相关的VS下降，从而为基本个体的护理预防做出了贡献。（3）在最佳妇女中进行定期运动会带来各种好处，例如体内脂肪的减少，骨骼质量增加，预防动脉硬化和平衡能力。（4）适当的运动可以改善健康基本个体的多个（身体，代谢和心理）功能。（5）对于定期运动的基本人来说，过去的秋季历史，绊倒和年龄是未来跌倒的独立预测指标。 [○！6]从动物研究中，定期运动可以通过增加抗氧化能力来防止动脉粥样硬化。我们的研究建立了一种有用的措施来评估健康中年和老年人的质量。生命力量表将带来好处，以确定可能处于谨慎身份的脆弱人群。通过这种量表，运动被证明可以防止与年龄相关的VS下降。我们还能够证明锻炼可以提供各种益处，例如抗动脉粥样硬化作用和骨骼质量增加。我们仍在追求这个队列，并希望继续获得有关锻炼影响的重要数据。