Development of intraoperative monitoring system for spinal function

脊柱功能术中监测系统的研制

• 批准号: 15360049
• 负责人: HARA Toshiaki
• 金额: $ 9.66万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15360049/
• 关键词: Biomechanics; Insuturumentation; Medical insuturument; Spine; Stiffness; Intraoperative measurement; Strength of biomaterials; Degeneration; 組織変成; バイオメカニクス; 術中モニター; 手術支援; 脊椎不安定症; 腰椎; 椎間板; 圧力測定; 脊椎機能損傷; インスツルメンツ; 脊椎組織変性; 微小運動

Although computer assisted navigation system are widely used in the treatment of spinal disease in order to minimize the operational damage to the surrounding tissue, the biomechanically spinal joint motion including the degenerative tissue has been insignificantly understood. Instability in the lumbar spinal motion segment (vertebra-disc-vertebra) is noted to be an important factor of spinal disorders. Radiographic or basic biomechanical research for definition of the segmental instability has been well documented. However, some contraversial definitions have been consistently demonstrated.In this project research, to evaluate quantitative spinal mobility and to justify lumber fusion or stabilization, an intraoperative and special designed measurement system has been developed. The system used for measuring spinal segmental mobility is consisted of three segments, spinous process holders, motion generator, and computerized controller. The spinous holders make it possible to handle spinal process without invasiveness for the supra- and inter-spinous ligaments. A continuous displacement that generated from actuator of motion generator at speed of 2.0 mm/s is given to the tip of the spinous processes holders. Measurements of human spinal mobility were made on 24 spinal motion segments in 23 patients with degenerative lumbar disease. (12 men and 11 women) including : 8 segments discopathy, 11 segments spondylitis deformans, 5 segments lumbar spinal canal stenosis. Patient ages ranged from 21 to 83 years (average, 57 years).Each measurement took only about ten minutes on average. Load-displacement curves during spinal segmental motion were recorded with excellent reproducibility. In clinical experiment and conclusion, this system is a accurate tool for measuring intraoperative spinal function. It can be used to evaluate sufficiently the degenerative charasiteristics of spinal segment, and to make pre and post disorder measurements.

尽管计算机辅助导航系统被广泛用于治疗脊柱疾病，以最大程度地减少对周围组织的操作损害，但包括退化组织在内的生物力学上的脊柱关节运动已被微不足道地理解。腰椎运动段（椎骨 - 椎间盘）中的不稳定性被认为是脊柱疾病的重要因素。有充分的文献记录了用于定义节段性不稳定的放射学或基本生物力学研究。但是，已经始终证明了一些相关的定义。在这项项目研究中，为了评估定量脊柱迁移率并证明木材融合或稳定是合理的，已经开发了术中和特殊设计的测量系统。用于测量脊柱分段迁移率的系统包括三个段，棘突架，运动发生器和计算机控制器。棘突持有者使得可以处理脊柱过程，而无需侵入性棘突间韧带。以2.0 mm/s的速度从动作发生器执行器产生的连续位移被给予棘突支架的尖端。在23例退行性腰椎疾病患者中，对24个脊柱运动段进行了人脊柱迁移率的测量。 （12名男性和11名女性），包括：8个片段，有11个段落，11个段脊柱炎，5个部分腰椎管狭窄。患者年龄从21至83岁不等（平均57岁）。每个测量平均仅需十分钟。记录了脊柱节段运动期间的负载置换曲线，具有出色的可重复性。在临床实验和结论中，该系统是测量术中脊柱功能的准确工具。它可用于充分评估脊柱段的退化性炭化性，并进行疾病前后的测量。

项目成果

村田冬樹: "ナノインデンテーションを用いたウシ椎体シェルの弾性率および硬さの測定"第30回日本臨床バイオメカニクス学会抄録集. 30. 52-52 (2003)

Fuyuki Murata：“使用纳米压痕测量牛椎体壳的弹性模量和硬度”第 30 届日本临床生物力学学会会议记录 30. 52-52 (2003)。

The difference of mechanical influence on lamina using Ti cable or PE cable for Sublaminar Wiring

层内布线使用Ti电缆和PE电缆对层板机械影响的差异

• 发表时间: 2005
• 期刊: Japanese Journal of Clinical Biomechanics Vol.26
• 作者: 北原 恒;高野 光;原 利昭;O.Sajiki
• 通讯作者: O.Sajiki

Evaluation of rotational mobility and characteristics for intradiscal pressure in an instability model of spine

脊柱不稳定性模型中旋转活动度和椎间盘内压力特征的评估

• 发表时间: 2005
• 期刊: Proc.of the 18^<th> Bioengineering Conference, 2005 Annual Meeting og BE D/JSME No.05-66
• 作者: 北原 恒;高野 光;原 利昭;O.Sajiki;K.Kitahara;K.Kitahara;K.Kitahara;O.Sajiki
• 通讯作者: O.Sajiki

腰椎可動性測定システム

腰椎活动度测量系统

• 发表时间: 2005

術中可動性測定器を用いたヒト腰椎の運動特性評価に関する研究

术中活动度测量装置评估人体腰椎运动特性的研究

• 发表时间: 2004
• 期刊: 日本臨床バイオメカニクス学会誌 Vol.25
• 作者: 北原 恒;高野 光;原 利昭;北原 恒;北原 恒
• 通讯作者: 北原 恒