Development of intraoperative monitoring system for spinal function

脊柱功能术中监测系统的研制

基本信息

  • 批准号:
    15360049
  • 负责人:
  • 金额:
    $ 9.66万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 财政年份:
    2003
  • 资助国家:
    日本
  • 起止时间:
    2003 至 2005
  • 项目状态:
    已结题

项目摘要

Although computer assisted navigation system are widely used in the treatment of spinal disease in order to minimize the operational damage to the surrounding tissue, the biomechanically spinal joint motion including the degenerative tissue has been insignificantly understood. Instability in the lumbar spinal motion segment (vertebra-disc-vertebra) is noted to be an important factor of spinal disorders. Radiographic or basic biomechanical research for definition of the segmental instability has been well documented. However, some contraversial definitions have been consistently demonstrated.In this project research, to evaluate quantitative spinal mobility and to justify lumber fusion or stabilization, an intraoperative and special designed measurement system has been developed. The system used for measuring spinal segmental mobility is consisted of three segments, spinous process holders, motion generator, and computerized controller. The spinous holders make it possible to handle spinal process without invasiveness for the supra- and inter-spinous ligaments. A continuous displacement that generated from actuator of motion generator at speed of 2.0 mm/s is given to the tip of the spinous processes holders. Measurements of human spinal mobility were made on 24 spinal motion segments in 23 patients with degenerative lumbar disease. (12 men and 11 women) including : 8 segments discopathy, 11 segments spondylitis deformans, 5 segments lumbar spinal canal stenosis. Patient ages ranged from 21 to 83 years (average, 57 years).Each measurement took only about ten minutes on average. Load-displacement curves during spinal segmental motion were recorded with excellent reproducibility. In clinical experiment and conclusion, this system is a accurate tool for measuring intraoperative spinal function. It can be used to evaluate sufficiently the degenerative charasiteristics of spinal segment, and to make pre and post disorder measurements.
尽管计算机辅助导航系统广泛用于脊柱疾病的治疗,以尽量减少对周围组织的操作损伤,但包括退行性组织在内的生物力学脊柱关节运动的了解却很少。腰椎运动节段(椎-椎间盘-椎)的不稳定被认为是脊柱疾病的一个重要因素。用于定义节段不稳定性的放射线照相或基础生物力学研究已有详细记录。然而,一些相反的定义得到了一致的证明。在该项目研究中,为了评估定量脊柱活动性并证明腰椎融合或稳定的合理性,开发了一种术中且特殊设计的测量系统。用于测量脊柱节段活动度的系统由三部分组成:棘突支架、运动发生器和计算机控制器。棘状支架可以在不侵入棘上和棘间韧带的情况下处理脊柱过程。运动发生器的致动器以 2.0 mm/s 的速度产生连续位移到棘突支架的尖端。对 23 名退行性腰椎疾病患者的 24 个脊柱运动节段进行了人类脊柱活动度的测量。 (男12例,女11例)包括:椎间盘病变8节段,变形性脊柱炎11节段,腰椎管狭窄5节段。患者年龄从21岁到83岁不等(平均57岁)。每次测量平均只需要大约10分钟。记录脊柱节段运动期间的负载-位移曲线,具有良好的再现性。从临床实验和结论来看,该系统是术中脊柱功能测量的准确工具。它可用于充分评估脊柱节段的退变特征,并进行病变前后的测量。

项目成果

期刊论文数量(35)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
村田冬樹: "ナノインデンテーションを用いたウシ椎体シェルの弾性率および硬さの測定"第30回日本臨床バイオメカニクス学会抄録集. 30. 52-52 (2003)
Fuyuki Murata:“使用纳米压痕测量牛椎体壳的弹性模量和硬度”第 30 届日本临床生物力学学会会议记录 30. 52-52 (2003)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
The difference of mechanical influence on lamina using Ti cable or PE cable for Sublaminar Wiring
层内布线使用Ti电缆和PE电缆对层板机械影响的差异
Evaluation of rotational mobility and characteristics for intradiscal pressure in an instability model of spine
脊柱不稳定性模型中旋转活动度和椎间盘内压力特征的评估
腰椎可動性測定システム
腰椎活动度测量系统
  • DOI:
  • 发表时间:
    2005
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
術中可動性測定器を用いたヒト腰椎の運動特性評価に関する研究
术中活动度测量装置评估人体腰椎运动特性的研究
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HARA Toshiaki其他文献

HARA Toshiaki的其他文献

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{{ truncateString('HARA Toshiaki', 18)}}的其他基金

Folding of cysteine-rich peptides on phospholipid membrane
富含半胱氨酸的肽在磷脂膜上的折叠
  • 批准号:
    24651242
  • 财政年份:
    2012
  • 资助金额:
    $ 9.66万
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Development of a method for purification of membrane proteins by photocleavable linkers.
开发通过光裂解接头纯化膜蛋白的方法。
  • 批准号:
    22710216
  • 财政年份:
    2010
  • 资助金额:
    $ 9.66万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
An integrated study on RP technique aided hard surgery
RP技术辅助硬质手术的综合研究
  • 批准号:
    18360057
  • 财政年份:
    2006
  • 资助金额:
    $ 9.66万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Development of the functional bad bearing device for hip joint
髋关节功能性不良轴承装置的研制
  • 批准号:
    12794021
  • 财政年份:
    2000
  • 资助金额:
    $ 9.66万
  • 项目类别:
    Grant-in-Aid for University and Society Collaboration
Biomechanical Analysis of Sensibility Variation with Aging
敏感性随衰老变化的生物力学分析
  • 批准号:
    09680849
  • 财政年份:
    1997
  • 资助金额:
    $ 9.66万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Analysis of Human Sensitivity using Pressure Sensitive Rubber Sensors
使用压敏橡胶传感器分析人体敏感性
  • 批准号:
    04452120
  • 财政年份:
    1992
  • 资助金额:
    $ 9.66万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (B)
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