Development of the functionally graded polymer material by which the dentin can be replaced

可替代牙本质的功能梯度高分子材料的开发

• 批准号: 13680960
• 负责人: SANO Yuuko
• 金额: $ 0.19万
• 依托单位: Meirin Junior Collrge, School of Dental Technology, Hygiene and Welfare
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13680960/
• 关键词: Electron beam heating irradiation; Inclinable high molecular material; Available polycarbonate artificial teeh; Physico chemical test; Amid polymer; アミドポリマー; 硬度; 原子間力顕微鏡; 接触角; 吸水率; グルコース付着量; 細胞毒性試験; 加熱電子線照射; 高分子材料; 傾斜性付与; 酸素障害; 窒素等不活性ガス雰囲気

This report summarizes our recent research and development made on the functionally graded polymer material whose dentin can be replaced by reforming high molecular material by controlling electron dose (absorption dose, linear energy transfer ratio). High molecular material that has an inclination with hardness imparted to the vicinity of the outer surface has been developed by applying electron beams with the viscoelasticity of high molecular material maintained.Literature searching was carried out on radiation degradation which would cause interference to our study. Based on this, basic experiments were carried out on radiation degradation under coexistence of oxygen of high molecular material and the permissible value was set to 2730 ppm or lower for residual oxygen concentration.For electron beam heating irradiation test of the present study, a radiation exposure jig was devised, designed, and fabricated. Special consideration was given to the radiation exposure jig so that smooth … More inert gas replacement can take place in order to prevent oxygen electrode injury when radiation I s applied.For specimens used in the present study, polycarbonate polymer and amide polymer were chosen, which have been popularly used in the medical field and exhibit cross-linking reactions by radiation.Hardness was measured as a yardstick for the reforming effects. Specimens were prepared, set in the radiation exposure jig, heated to glass transition temperature, and irradiated with electron beams in vacuum or inert gas atmosphere, and reforming effects were measured.The surface properties of specimens with inclination imparted were observed, contact angle was measured, and water absorption ratio as well as dextrose adhesion dosage were measured.In addition, of the physicochemical tests and bisphenol-A assay were carried out The results were presented and reviewed at the 24th Annual Meeting of the Japanese Society for Biomaterials.In order to determine the possibility of putting it into practical use, heated radiation test was carried out on commercially available polycarbonate artificial teeth, which were heated and irradiated with electron beams under nitrogen gas atmosphere,and it has been verified that inclination is imparted to the teeth.The results of practical use experiment as well as physicochemical test and biological safety test results were evaluated generally, and the usefulness of the results of the present study was discussed, and the research report was summarized. Less

该报告总结了我们对功能分级的聚合物材料的最新研究和开发，可以通过控制电子剂量（吸收剂量，线性能量转移比）来代替牙本质。通过施加具有高分子材料的粘弹性的电子束，在辐射降解时进行了探索，这会导致干扰我们的研究，从而开发了具有硬度倾斜度的高分子材料，该材料具有硬度赋予外表面附近的倾斜度。基于这一点，在高分子材料的氧气共存下进行了基本实验，并将允许值设置为2730 ppm或更低，以使残留的氧浓度进行。对于本研究的电子束加热测试，设计了辐射暴露夹具，设计并制造了辐射夹具。对辐射暴露的夹具进行了特殊考虑，以使其平滑……可以进行更平滑的液体更换，以防止施加辐射时进行氧气损伤。用于本研究中使用的样品，选择了多碳酸盐聚合物和酰胺聚合物，这些样本被选择在医疗领域中被广泛使用，并且是通过跨度的反应来进行的。准备在辐射暴露夹具中设置，加热到玻璃过渡温度，并用电子束在真空或惰性气体大气中受辐射，并测量重整效果。观察到具有倾斜度的样品的表面性能，测量接触角，测量接触角，并吸收比以及测试剂的粘合剂剂量，并确定了粘合剂量。在日本生物材料学会的第24届年会上提出和审查了结果。为了确定将其置于实际使用的可能性，在商业上可用的多碳酸盐人造牙齿上进行了加热辐射测试，这些牙齿被加热和辐射，并在氮气气氛中使用了牙齿，并在物理上使用了牙齿，并验证了练习，并以验证效果。一般评估了生物安全测试结果，并讨论了本研究结果的有用性，并总结了研究报告。较少的

项目成果

T.Seguchi, T.Yagi, S.Ishikawa, Y.Sano: "New material synthesis by radiation processing at high temperature - polymer modiflcationwith improved irrad iation technology"Radeation Physics and Chemistry. 63. 35-40 (2002)

T.Seguchi、T.Yagi、S.Ishikawa、Y.Sano：“高温辐射加工合成新材料——改进辐照技术的聚合物改性”辐射物理与化学。

T.Seguchi, T.Yagi, S.Ishikawa, Y.Sano: "New material synthesis by radiation processing at high temperature -polymer modification with improved irradiation technology"Radiation Physics and Chemistry. 63. 35-40 (2002)

T.Seguchi、T.Yagi、S.Ishikawa、Y.Sano：“高温辐射加工合成新材料——改进辐照技术的聚合物改性”《辐射物理与化学》。