Assessment of biological effect of low dose butyltin concentrations using small crustaceans with short-life span

使用寿命短的小型甲壳类动物评估低剂量丁基锡浓度的生物效应

• 批准号: 12680540
• 负责人: TAKEUCHI Ichiro
• 金额: $ 2.24万
• 依托单位: Ehime University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680540/
• 关键词: Biological Effect; Caprella; Crustacea; End point; Endocrine Disrupter Compound; Low Doze; TBT; 内分泌撹乱物質; 有機スズ化合物

Of many artificial chemicals which are though to have endocrine disruptor effects, the concern over the serious ecotoxicological impact of tribtyltin (TBT) led to legal restrictions on the usage of TBT in aquaculture and small boats in the majority of developed countries. Caprella spp.are small amphipod crustaceans with reduced movement and a life-span of less than 3 months. Moreover, Caprella spp.have lack the ability of degenerating TBT (tributyltin). These characteristics indicate that Caprella spp.are one of the most sensitive marine invertebrates to TBT. The field survey from the western part of Seto Inland Sea and adjacent areas on the butyltins during 2001 indicated that the TBT ranged N.D.(not detected) to 39.1 ng TBT/L. To assess the biological effect of TBT to Caprella., juveniles of Caprella danilevskii, which had been exposed to 5 concentrations from 0 to 10,000 ng TBTCl/L during embryonic development, reared in non-contaminated seawater more than 1 generation. The survival rate at the mature stage was less than 50 % even at 10 ng TBTCl/L. Thus, the TBT concentrations detected from the Seto Inland Sea during 2001 still influenced the survival rate of Caprella spp.

尽管具有内分泌破坏效应的许多人造化学物质，对Tribtyltin（TBT）严重的生态毒理学影响的关注导致对大多数发达国家中TBT使用TBT的法律限制。 Caprella spp。是小小的两亲甲壳动物，运动减少，寿命不到3个月。此外，Caprella spp。缺乏退化TBT（tributyltin）的能力。这些特征表明Caprella spp。这是TBT最敏感的海洋无脊椎动物之一。 2001年，丁托内海西部和丁丁蛋白上邻近地区的现场调查表明，TBT范围为N.D.（未检测到）至39.1 ng tbt/l。为了评估TBT对Caprella的生物学作用，Caprella danilevskii的少年在胚胎发育过程中暴露于5至10,000 ng tbtcl/L的5个浓度，在未污染的海水中饲养的海水饲养超过1代。即使在10 ng tbtcl/L处，成熟阶段的存活率也小于50％。因此，2001年从SETO内陆检测到的TBT浓度仍然影响Caprella属的存活率。

项目成果

Takeuchi, I., S.Takahashi, S.Tanabe, N.Miyazaki: "Caprella watch ; a new approach for monitoring butyltin residues in the ocean"Marine Environmental Research. 52・2. 97-113 (2001)

Takeuchi, I., S.Takahashi, S.Tanabe, N.Miyazaki：“Caprella 观察；监测海洋中丁基锡残留物的新方法”海洋环境研究 52・2 (2001)。

Takeuchi,I. et al.: "Caprella watch ; a new approach for monitoring butyltin residues in the ocean."Marine Environmental Research. (印刷中). (2001)

Takeuchi, I. 等人：“Caprella 观察；监测海洋中丁基锡残留物的新方法。”海洋环境研究（2001 年）。