Clinical Evalution of Antnior Mandibular Positioning Device for Patients with Obstructive Sleep Apnea

前下颌定位装置治疗阻塞性睡眠呼吸暂停的临床评价

基本信息

批准号：
12671897
负责人：
MASUMI Shin-ichi
金额：
$ 1.98万
依托单位：
Kyushu Dental College
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2001
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671897/
关键词：
Obstructive Sleep Apnea Sleep Splint Polysomnography Cliflical Evaluation スプリント

项目摘要

The purpose of this study is to evaluate two fabrication methods (direct method, indirect method) of a simple AMP and evaluate its treatment effect for the patients with OSAS by using polysomnography (PSG)and Epworth sleepiness scale (ESS) bifore and after AMP therapy.Thera Snore TM (Distar) was used as AMP in this:study. Fabrication method of this AMP was indicated a direct method by manufacturer. We designed a inderect methoc and compared with a direct mothod. To evaluate the treatment eggect of this AMP five OSAS patients (4 males and 1 female) were involved. Mean age was 59.8 Years and body mass index (BMI) was 26.1. Each patient underwent PSG and ESS befor and after AMP therapy and evaluated about apnea index (AI),apnea-hypopnea index (AHI), Lowest SpO2, arousal index, and ESS.Indirect fabrication method was better than direct method from the viewpoint of the fitness and the protection of mucous membrane from scald. AI was improved from 5.5 +/- 4.04 to 2.3 +/- 3.86. AHI was improved 20.8 +/- 14.99 to 8.8 +/- 9.04. Lowest SpO2 was improved from 8l.0 +/- 9.08 to 86.6 +/ -6.73 %. Arousal index improved 31.6 +/- 10.26 to 25.5 +/- 10.37. ESS was improved from 10.6 +/- 1.95 to 6.0 +/- 3.08.It was suggested hat the indirect method was better than the direct method for fabricating the AMP which used in this study. It was also suggested that this AMP was useful for the treatment of the patients with OSAS.

本研究的目的是评估简单AMP的两种制作方法（直接法、间接法），并在AMP治疗前后使用多导睡眠图（PSG）和Epworth嗜睡量表（ESS）评估其对OSAS患者的治疗效果.Thera Snore TM (Distar) 在本研究中用作 AMP。该 AMP 的制造方法由制造商指定为直接方法。我们设计了一种间接方法并与直接方法进行了比较。为了评估该 AMP 的治疗效果，涉及 5 名 OSAS 患者（4 名男性和 1 名女性）。平均年龄为 59.8 岁，体重指数 (BMI) 为 26.1。每个患者在 AMP 治疗前后均接受 PSG 和 ESS，并评估呼吸暂停指数（AI）、呼吸暂停低通气指数（AHI）、最低 SpO2、觉醒指数和 ESS。健身及保护粘膜免遭烫伤。 AI 从 5.5 +/- 4.04 提高到 2.3 +/- 3.86。 AHI 改善了 20.8 +/- 14.99 至 8.8 +/- 9.04。最低 SpO2 从 8l.0 +/- 9.08 改善至 86.6 +/-6.73 %。唤醒指数从 31.6 +/- 10.26 提高到 25.5 +/- 10.37。 ESS 从 10.6 +/- 1.95 提高到 6.0 +/- 3.08。表明本研究中使用的间接方法比直接方法制造 AMP 更好。还表明该 AMP 对于治疗 OSAS 患者很有用。