Development of New strategy to treat velopharyngeal dysfunction for stroke with combination of a palatal lift, and CPAP

开发联合上腭提升和 CPAP 治疗中风腭咽功能障碍的新策略

• 批准号: 12671879
• 负责人: WADA Takeshi
• 金额: $ 1.98万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671879/
• 关键词: stroke; speech appliance; dysarthria; velopharynx; levator veli palatini; rehabilitation; nasal air pressure; 運動療法; スピーチェイド; 音声言語

The study was aimed to examine whether new strategy to improve velopharyngeal function for stroke patients by means of CPAP (Continues Positive Air Pressure) with support of a palatal lift prosthesis to decrease fatigability of the related muscles.The results obtained here as follows:1. Levator veli palatini muscle activity (% peak levator activity) was ranged in a bipolar manner; For some speech sounds, the range was estimated to be closed to 100 % of the possible maximum activity level while for other sounds it was no or less.2. There was no tendency in the characteristics of bipolar manner across speech sounds. The aspect of bipolar manner was variable even for same speech sounds for each subject.3. The smoothed levator veli palatini muscle activity was tended to be stabilized with a PLP in place while it was variably change d in association with number of production of speech.4. The fatigability of the levator veli palatini muscle was identified to be decreased by placement of a PLP by mean of FFT analysis of MPF (Mean Power Frequency)5. Experimental CPAP was proved to activate levator muscle activity in the condition of a PLP. Some patient showing active response to induced GPAP was indicated to be candidate for home treatment of CPAP with a PLP in place.6. The response of home CPAP therapy was variable across candidates: Significant response was showed by subjects with young age and/or good management after onset of stroke.

该研究的目的是研究通过CPAP（持续气压持续）支持palatal升力假体以减少相关肌肉疲劳性的新策略是否通过CPAP（持续气压持续）来改善咽咽功能。左旋杆菌palatini肌肉活性（％峰值左右活性）以双极性方式范围；对于某些语音，估计该范围已关闭到可能的最大活动水平的100％，而对于其他声音，则没有或多或少。2。在语音上，双极方式的特征没有趋势。即使对于每个受试者，双极方式的方面也是可变的。3。平滑的左旋武器Veli palatini肌肉活动倾向于用PLP稳定在适当的位置，而随着语音的产生数量，它会变化。4。通过平均MPF分析（平均功率频率）5的平均值，可以通过放置PLP来识别出左旋武器palatini肌肉的疲劳性。事实证明，实验性CPAP在PLP的条件下激活了悬臂肌肉活性。一些患者表现出对诱导GPAP的主动反应的患者被表明是使用PLP的CPAP进行家庭治疗的候选。6。在候选人中，家庭CPAP治疗的反应是可变的：中风发作后具有年轻和/或良好管理的受试者表明了重大反应。

项目成果

TACHIMURA, T., et al.: "Effect of placement of a speech appliance on levator veli palatini muscle activity during speech"Cleft Palate-Craniofacial Journal. 37・5. 478-482 (2000)

TACHIMURA, T., et al.：“言语器具的放置对言语过程中提肌腭肌活动的影响”Cleft Palate-Craniofacial Journal 37・5 (2000)。

Tachimura, T., Nohara, K, Fujita, Y, et al.: "Change in levator veli palatini muscle activity for patients with cleft palate in association with placement of a speech-aid prosthesis."Cleft Palate-Craniofatial Journal. 39(5). 503-508 (2002)

Tachimura, T.、Nohara, K、Fujita, Y 等人：“腭裂患者的提腭帆肌活动变化与言语辅助假体的放置相关。”Cleft Palate-Craniofatial Journal。

野村幹司, 舘村卓, 他: "嚥下時,発音時,blowing時における口蓋帆挙筋活動の相違-筋電図信号の周波数解析を用いた検討-"日本摂食嚥下リハビリテーション学会雑誌. 6・2. 37-43 (2002)

Mikiji Nomura、Taku Tatemura 等人：“吞咽、发音和吹气时提腭帆肌活动的差异 - 使用肌电图信号频率分析的研究 -”日本饮食和吞咽康复学会杂志 6・2。 37-43（2002）

Nohara, K, Tachimura, T., Fujita, Y., et al.: "Power spectra analysis of electromyogram of the levator veil palatini muscle during velophaiyngeal closure for swallowing, speech and blowing."Jpn J. of Dysphagia Rehabil. 6(2). 37-43 (2002)

Nohara, K, Tachimura, T., Fujita, Y., et al.：“吞咽、言语和吹气闭合腭咽闭合过程中提肌面纱肌电图的功率谱分析。”Jpn J. of Dysphagia Rehabil。

Nohara, K, Tachimura, T., Wada, T.: "Evaluation of Levator Veli Palatini Muscle Fatigue Using Mean Power Frequency."J. Jpn. Cleft Palate Assoc.. 26. 333-338 (2001)

Nohara, K、Tachimura, T.、Wada, T.：“使用平均功率频率评估提肌 Veli Palatini 肌肉疲劳。”J。