Epidemiological study on osteoarthritis among community-dwelling women

社区女性骨关节炎流行病学研究

• 批准号: 11670374
• 负责人: AOYAGI Kiyoshi
• 金额: $ 2.18万
• 依托单位: NAGASAKI UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11670374/
• 关键词: osteoarthritis; joint pain; aging; epidemiology; community Health; 危険因子

We studied 591 women living in Oshima town, Nagasaki Prefecture, Japan on the prevalence of osteoarthritis and joint pains and its association. Information on painful joints was collected by questionnaire. Subjects were asked Which of your joints have ever been painful, swollen, aching, or tender on most days for the past one month? Response boxes (yes and no) for both sides of the body were provided on an illustration of the skeleton for each joint (shoulders, elbows, wrists, hands/fingers, hips knees, ankles, feet, neck, upper back, mid-back, and low back). Radiographs were obtained of knees (antero-posterior weightbearing). Height and weight were measured, and body mass index (BMI) was calculated. Knee (34.8%), low back (26.6%) and shoulder (16.4%) pain were the most prevalent locations of joint pain. One third of women had radiographic osteoarthritis of the knee. None of the women had radiographic knee osteoarthritis in age group of 40-49 years, but the prevalence increased with age, and 60% of women had knee osteoarthritis in age group of 80 and over. Twenty percent of the women had symptomatic knee osteoarthritis. The prevalence increased with age, and 40% had symptomatic knee osteoarthritis. Multiple variable logistic regression analysis revealed that radiographic or symptomatic knee osteoarthritis was associated with increasing age, obesity, history of knee injury and increased phsical activity. Previous studies have been reported that increasing age, obesity and history of knee injury were risk factors for knee osteoarthritis, which is consistent with our results. Increased physical activity may attribute to development of knee osteoarthritis through additive loading to joint cartilage.

我们对居住在日本长崎县大岛镇的 591 名女性进行了研究，了解骨关节炎和关节疼痛的患病率及其关联性。通过问卷调查收集有关疼痛关节的信息。受试者被问及在过去一个月的大部分时间里，你的哪个关节曾经感到疼痛、肿胀、酸痛或压痛？每个关节（肩膀、肘部、手腕、手/手指、臀部、膝盖、脚踝、脚、颈部、上背部、中背部）的骨骼插图上提供了身体两侧的回答框（是和否）和下背）。获得膝盖的射线照片（前后负重）。测量身高和体重，并计算体重指数（BMI）。膝盖（34.8%）、腰部（26.6%）和肩部（16.4%）疼痛是最常见的关节疼痛部位。三分之一的女性患有放射学膝关节骨关节炎。在40-49岁年龄组中，没有女性患有膝骨关节炎，但患病率随着年龄的增长而增加，在80岁及以上年龄组中，60%的女性患有膝骨关节炎。百分之二十的女性患有有症状的膝骨关节炎。患病率随着年龄的增长而增加，40%的人患有有症状的膝骨关节炎。多变量逻辑回归分析显示，放射学或有症状的膝骨关节炎与年龄增长、肥胖、膝关节损伤史和体育活动增加有关。先前的研究报道，年龄增长、肥胖和膝关节损伤史是膝骨关节炎的危险因素，这与我们的结果一致。体力活动的增加可能会通过关节软骨的附加负荷而导致膝骨关节炎的发生。

项目成果

Aoyagi K. et al.: "Calcaneus bone mineral density is lower among men and women with lower physical performance"Calcif Tissue Int. 67(2). 106-110 (2000)

Aoyagi K. 等人：“身体机能较低的男性和女性的跟骨骨矿物质密度较低”Calcif Tissue Int.

Yoshida M. et al.: "Urinary sodium/potassium ratio and prevalence of hypertension in two communities of different historical origin in Oshima island, Nagasaki, Japan"Ecol Food Nutr. 39. 183-198 (2000)

Yoshida M.等人：“日本长崎大岛两个不同历史起源社区的尿钠/钾比值和高血压患病率”Ecol Food Nutr。

Aoyagi K.Ross PD, Hayashi T, Okano K, Moji K, Sasayama H, Yahata Y, Takemoto T.: "Calcaneus bone mineral density is lower among men and women with lower physical performance"Calcif Tissue Int.. 67(2). 106-110 (2000)

Aoyagi K.Ross PD、Hayashi T、Okano K、Moji K、Sasayama H、Yahata Y、Takemoto T.：“身体机能较低的男性和女性跟骨骨矿物质密度较低”Calcif Tissue Int.. 67(2)

Yoshida M. et al.: "Urinary sodium/potassium ratio prevalence of hypertension in two communities of different historical origin in Oshima island, Nagasaki, Japan"Ecol Food Nutr. 39. 183-198 (2000)

Yoshida M.等人：“日本长崎大岛两个不同历史起源社区的高血压尿钠/钾比患病率”Ecol Food Nutr。

青柳 潔 他: "成人女性の前腕骨骨塩量とライフスタイルの年代別特徴"長崎医学会雑誌. (印刷中).

Kiyoshi Aoyagi 等：“成年女性前臂骨矿物质密度和生活方式的特征”，长崎医学会杂志（出版中）。