Epidemiological study on osteoarthritis among community-dwelling women

社区女性骨关节炎流行病学研究

• 批准号: 11670374
• 负责人: AOYAGI Kiyoshi
• 金额: $ 2.18万
• 依托单位: NAGASAKI UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11670374/
• 关键词: osteoarthritis; joint pain; aging; epidemiology; community Health; 危険因子

We studied 591 women living in Oshima town, Nagasaki Prefecture, Japan on the prevalence of osteoarthritis and joint pains and its association. Information on painful joints was collected by questionnaire. Subjects were asked Which of your joints have ever been painful, swollen, aching, or tender on most days for the past one month? Response boxes (yes and no) for both sides of the body were provided on an illustration of the skeleton for each joint (shoulders, elbows, wrists, hands/fingers, hips knees, ankles, feet, neck, upper back, mid-back, and low back). Radiographs were obtained of knees (antero-posterior weightbearing). Height and weight were measured, and body mass index (BMI) was calculated. Knee (34.8%), low back (26.6%) and shoulder (16.4%) pain were the most prevalent locations of joint pain. One third of women had radiographic osteoarthritis of the knee. None of the women had radiographic knee osteoarthritis in age group of 40-49 years, but the prevalence increased with age, and 60% of women had knee osteoarthritis in age group of 80 and over. Twenty percent of the women had symptomatic knee osteoarthritis. The prevalence increased with age, and 40% had symptomatic knee osteoarthritis. Multiple variable logistic regression analysis revealed that radiographic or symptomatic knee osteoarthritis was associated with increasing age, obesity, history of knee injury and increased phsical activity. Previous studies have been reported that increasing age, obesity and history of knee injury were risk factors for knee osteoarthritis, which is consistent with our results. Increased physical activity may attribute to development of knee osteoarthritis through additive loading to joint cartilage.

我们研究了日本长崎县奥岛镇的591名妇女，以了解骨关节炎和关节疼痛及其关联的盛行。问卷收集了有关疼痛关节的信息。在过去一个月的大多数日子里，受试者被问到您的哪个关节曾经痛苦，肿胀，疼痛或温柔？在每个关节的骨骼（肩膀，肘部，手腕，手/手指，臀部膝盖，脚踝，脚踝，脚，脖子，颈部，上背部，中背部和下背部）的骨骼插图上，提供了身体两侧的响应盒（是和否）。射线照片是膝盖的（前后重量）。测量身高和体重，并计算体重指数（BMI）。膝盖（34.8％），腰背（26.6％）和肩膀（16.4％）疼痛是关节疼痛的最普遍的位置。三分之一的女性患有膝关节射线照相骨关节炎。没有一个女性在40-49岁的年龄组中患有射线照相骨关节炎，但患病率随着年龄的增长而增加，在80岁及以上的年龄组中，有60％的女性患有膝关节骨关节炎。 20％的女性患有症状性的膝关节骨关节炎。患病率随着年龄的增长而增加，有40％的膝关节骨关节炎。多变量的逻辑回归分析表明，射线照相或有症状的膝关节骨关节炎与年龄升高，肥胖症，膝盖损伤病史和pHSical活性增加有关。先前的研究据报道，年龄，肥胖和膝关节损伤病史的增加是膝关节骨关节炎的危险因素，这与我们的结果一致。体育锻炼的增加可能归因于通过添加剂负荷的关节软骨的发育。

项目成果

Aoyagi K. et al.: "Calcaneus bone mineral density is lower among men and women with lower physical performance"Calcif Tissue Int. 67(2). 106-110 (2000)

Aoyagi K. 等人：“身体机能较低的男性和女性的跟骨骨矿物质密度较低”Calcif Tissue Int.

Yoshida M. et al.: "Urinary sodium/potassium ratio and prevalence of hypertension in two communities of different historical origin in Oshima island, Nagasaki, Japan"Ecol Food Nutr. 39. 183-198 (2000)

Yoshida M.等人：“日本长崎大岛两个不同历史起源社区的尿钠/钾比值和高血压患病率”Ecol Food Nutr。

Aoyagi K.Ross PD, Hayashi T, Okano K, Moji K, Sasayama H, Yahata Y, Takemoto T.: "Calcaneus bone mineral density is lower among men and women with lower physical performance"Calcif Tissue Int.. 67(2). 106-110 (2000)

Aoyagi K.Ross PD、Hayashi T、Okano K、Moji K、Sasayama H、Yahata Y、Takemoto T.：“身体机能较低的男性和女性跟骨骨矿物质密度较低”Calcif Tissue Int.. 67(2)

Yoshida M. et al.: "Urinary sodium/potassium ratio prevalence of hypertension in two communities of different historical origin in Oshima island, Nagasaki, Japan"Ecol Food Nutr. 39. 183-198 (2000)

Yoshida M.等人：“日本长崎大岛两个不同历史起源社区的高血压尿钠/钾比患病率”Ecol Food Nutr。

青柳 潔 他: "成人女性の前腕骨骨塩量とライフスタイルの年代別特徴"長崎医学会雑誌. (印刷中).

Kiyoshi Aoyagi 等：“成年女性前臂骨矿物质密度和生活方式的特征”，长崎医学会杂志（出版中）。