Evaluation of the viability of the transplanted bone glaft for alveolar cleft using blood flow measurement and SPECT

使用血流测量和 SPECT 评估牙槽裂移植骨移植的活力

基本信息

批准号：
10671859
负责人：
SAKAMOTO Maya
金额：
$ 1.86万
依托单位：
Tohoku University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 2000
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671859/
关键词：
cleft lip and or palate secondary bone grafting bone scintigraphy MRI Cleft lip and palate Radionuclide imaging Bone grafting SPECT Cleft lip and or palate

项目摘要

The purpose of this study was to assess the condition and viability of the autogenous particulate marrow and cancellous bone grafted for alveolar cleft. In this investigation, unsuccessful cases that showed marked bone resorption on CT images obtained 1 month after the operation were evaluated. The viability of bone grafts was documented by means of bone scintigraphy and MRI.1. On the scintigrams and MRI obtained 3 months after the operation, there was no evidence of acute inflammation in the operated alveolus. The scintigrams revealed the decreased uptake at the cleft region and the increased uptake at the adjacent alveolus of the cleft. The decreased uptake of the cleft area gradually became wider and clearer until 14 months after the operation. On the other hand, the increased uptake at the adjacent alveolus of the cleft still partially remained at 14 months after the operation.2. On T1-weighted MRI obtained 3 months after the operation of some cases, the grafted bone showed partially hyper intensity similar to the fatty tissues. This area extended to the adjacent alveolus on the MRI obtained 14 months after the operation.3. From these findings we suggest that scintigraphy may be useful to evaluate postoperative avascular necrosis in the alveolar cleft, and that MRI may be useful in assessing the fatty marrow maturation of the bone bridge.

这项研究的目的是评估自体颗粒骨髓和被牙槽裂缝的骨骨的状况和生存能力。在这项调查中，评估手术后1个月获得的CT图像上明显骨吸收的不成功病例。骨移植物的生存能力通过骨闪烁显像和MRI.1记录。在手术后3个月获得的闪烁液和MRI上，没有证据表明手术肺泡中急性炎症。闪烁液显示，裂缝区域的吸收减少，裂缝相邻肺泡的吸收增加。裂口区域的摄取减少逐渐变得越来越清晰，直到手术后14个月。另一方面，在手术后14个月内，裂口相邻肺泡的摄取增加仍然部分保留。2。在某些情况下3个月后获得的T1加权MRI，移植的骨骼显示出与脂肪组织相似的部分高强度。该区域延伸至手术后14个月获得的MRI的相邻肺泡3。从这些发现中，我们建议闪烁显像可用于评估肺泡裂缝中术后血管坏死，并且MRI对于评估骨桥的脂肪骨髓成熟可能很有用。