Evaluation of the viability of the transplanted bone glaft for alveolar cleft using blood flow measurement and SPECT

使用血流测量和 SPECT 评估牙槽裂移植骨移植的活力

基本信息

批准号：
10671859
负责人：
SAKAMOTO Maya
金额：
$ 1.86万
依托单位：
Tohoku University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 2000
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671859/
关键词：
cleft lip and or palate secondary bone grafting bone scintigraphy MRI Cleft lip and palate Radionuclide imaging Bone grafting SPECT Cleft lip and or palate

项目摘要

The purpose of this study was to assess the condition and viability of the autogenous particulate marrow and cancellous bone grafted for alveolar cleft. In this investigation, unsuccessful cases that showed marked bone resorption on CT images obtained 1 month after the operation were evaluated. The viability of bone grafts was documented by means of bone scintigraphy and MRI.1. On the scintigrams and MRI obtained 3 months after the operation, there was no evidence of acute inflammation in the operated alveolus. The scintigrams revealed the decreased uptake at the cleft region and the increased uptake at the adjacent alveolus of the cleft. The decreased uptake of the cleft area gradually became wider and clearer until 14 months after the operation. On the other hand, the increased uptake at the adjacent alveolus of the cleft still partially remained at 14 months after the operation.2. On T1-weighted MRI obtained 3 months after the operation of some cases, the grafted bone showed partially hyper intensity similar to the fatty tissues. This area extended to the adjacent alveolus on the MRI obtained 14 months after the operation.3. From these findings we suggest that scintigraphy may be useful to evaluate postoperative avascular necrosis in the alveolar cleft, and that MRI may be useful in assessing the fatty marrow maturation of the bone bridge.

本研究的目的是评估用于牙槽裂移植的自体颗粒骨髓和松质骨的状况和活力。在这项调查中，对手术后1个月获得的CT图像显示明显骨吸收的不成功病例进行了评估。通过骨闪烁扫描和 MRI 记录骨移植物的活力。1。术后3个月的闪烁图和MRI显示，手术肺泡没有急性炎症的证据。闪烁图显示裂口区域的摄取减少，而裂口邻近肺泡的摄取增加。直至术后14个月，裂口减少的摄取区域逐渐变宽和清晰。另一方面，术后14个月，裂隙邻近牙槽的摄取增加仍部分维持。2．部分病例术后3个月T1加权MRI显示，移植骨部分呈与脂肪组织相似的高强度。术后14个月的MRI显示该区域延伸至邻近的肺泡。 3．根据这些发现，我们认为闪烁扫描可能有助于评估牙槽裂术后缺血性坏死，而 MRI 可能有助于评估骨桥的脂肪骨髓成熟度。