Fluorescence Studies on Thermo-responsive Behavior and Microenvironment of Poly(N-alkylacrylamide) Gels

聚(N-烷基丙烯酰胺)凝胶热响应行为和微环境的荧光研究

基本信息

批准号：
10650867
负责人：
IWAI Kaoru
金额：
$ 0.26万
依托单位：
Nara Women's University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 1999
项目状态：
已结题

项目摘要

9-(4-N, N-Dimethylaminophenyl)phenanthrene (DMA-Phen ; DP), in which N, N-dimethylaniline (DMA) and phenanthrene (Phen) are linked directly by a single bond, shows an intense and structureless intramolecular charge-transfer (ICT) fluorescence. We have been interested in this compound DP as a new florescence probe because of its strong solvatochromism and have studied polymer microenvironments with using DP as an intramolecular fluorescence probe. In this project temperature-induced volume phase transitions of hydrogels prepared from acrylamide derivatives and their microenvironments have been studied by using the fluorescence probe technique. The results in this study are as follows.1.DP-labeled poly(N-isopropylacrylamide)(PNIPAM) hydrogels were prepared under various experimental conditions and temperature-induced phase transitions and microenvironments of them were studied by fluorescence probe technique.2.Some DP-labeled acrylamide polymer gels such as PNIPAM, poly(N, N-diethylacrylamide)(PDEAM), poly(N-isopropylmethacrylamide) (PNIPMAM), and poly(N, N-dimethylacrylamide) (PDMAM), were prepared and their temperature-induced phase transitions and microenvironments were compared with each other.3.DP-labeled NIPAM copolymer hydrogels with methyl methacrylate, DMAM, N-n-propylacrylamide, and NIPMAM were prepared. Thermo-responsive behaviors and microenvironments of copolymer gels were compared with each other.

9-(4-N,N-二甲基氨基苯基)菲 (DMA-Phen ; DP)，其中 N,N-二甲基苯胺 (DMA) 和菲 (Phen) 通过单键直接连接，显示出强烈且无结构的分子内电荷-转移（ICT）荧光。我们对这种化合物DP作为一种新型荧光探针很感兴趣，因为它具有很强的溶剂化显色性，并使用DP作为分子内荧光探针研究了聚合物微环境。在该项目中，利用荧光探针技术研究了由丙烯酰胺衍生物制备的水凝胶及其微环境的温度诱导的体积相变。本研究主要结果如下：1.在不同实验条件下制备了DP标记的聚N-异丙基丙烯酰胺(PNIPAM)水凝胶，并通过荧光探针技术研究了温度诱导的相变和微环境。2.一些研究成果DP标记的丙烯酰胺聚合物凝胶，例如PNIPAM、聚(N,N-二乙基丙烯酰胺)(PDEAM)、聚(N-异丙基甲基丙烯酰胺)(PNIPMAM)和制备了聚（N,N-二甲基丙烯酰胺）（PDMAM），并比较了它们的温度诱导相变和微环境。 3. DP标记的NIPAM与甲基丙烯酸甲酯、DMAM、N-正丙基丙烯酰胺和NIPMAM的共聚物水凝胶准备好了。对共聚物凝胶的热响应行为和微环境进行了相互比较。