System-level characterisation of the siphonophore, Indo-Pacific man o' war

印度-太平洋战争中管水母的系统级表征

• 批准号: DP220103933
• 负责人: Prof Greg Neely
• 金额: $ 40.73万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220103933
• 关键词: System; level; characterisation; siphonophore; Indo

The Indo-Pacific man o' war (bluebottle), is a cnidarian from the siphonophore order. These animals frequent Australian beaches in swarms and cause thousands of stings every year. The project proposes to profile the genome, transcriptome, epigenome, and proteome of the bluebottle to gain insight into its life cycle, its behaviour, and toxins. Expected outcomes include the generation of novel information related to bluebottle gene regulation and its toxin repertoire, which will be highly beneficial for the design of future sting treatment strategies. Given that the bluebottle is a colony made of functionally specialised polyps, this study will also provide significant novel insight into the origins and evolution of animal multicellularity.

印度太平洋战舰（bluebottle）是管水母目刺胞动物。这些动物成群结队地频繁出现在澳大利亚海滩，每年都会造成数千起蜇伤事件。该项目拟对蓝蝇的基因组、转录组、表观基因组和蛋白质组进行分析，以深入了解其生命周期、行为和毒素。预期结果包括产生与蓝蝇基因调控及其毒素库相关的新信息，这对于未来蜇伤治疗策略的设计非常有益。鉴于蓝瓶苍蝇是由功能特化的息肉组成的群体，这项研究还将为动物多细胞性的起源和进化提供重要的新见解。