Development of Implantable Electrode for Functional Electrical Stimulation.

用于功能性电刺激的植入式电极的开发。

基本信息

批准号：
06555197
负责人：
IGUCHI Yasutaka
金额：
$ 7.1万
依托单位：
TOHOKU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1996
项目状态：
已结题

项目摘要

The functional electrical stimulation (FES) system is very effective in order to restore motor functions of the paralyzed extremities in spinal cord injury and carebral disease patients. The applicants have been developed as stimulator with percutaneous intramuscular electrodes and have been utilizing clinically the system. However, this system has unavoidable problems such as infection and breakage at the position where electrodes go through skin, careful daily maintenance, and cosmetically unfavorable upon patients. Therefore, development of a totally implanted FES system is necessary. In this study more reliable electrodes have been developed than the present percutaneous electrodes. The obtained results are as follows :1. Chromium-cobalt alloy was refined by electro-slag remelting and 25 mum diameter wire was drawn as well as SUS316L stainless steel. The mechanical properties were well satisfied.2. Pitting corrosion was observed on the SUS316L wire in saline solution with accelerated corrosion test by applying electric current, on the contrary, no pitting corrosion on the 604PH wire.3. In order to easily and stably connect electrodes with the stimulator during operation, design of connectors and electrode tip were developed.4. Prototype systems of totally implanted FES with the electrodes of two kinds of materials (SUS316L and 604PH) were implanted in sheep and operating check of the system has been carried out. Useful information has been expected for development of the final system.

功能性电刺激（FES）系统非常有效，可以恢复脊髓损伤和保健疾病患者瘫痪的运动功能。申请人已被开发为具有经皮肌内电极的刺激剂，并一直在临床上使用该系统。但是，该系统存在不可避免的问题，例如感染和电极穿过皮肤的位置，仔细的每日维护以及对患者的外观不利的位置。因此，必须开发完全植入的FES系统。在这项研究中，比目前的经皮电极更可靠的电极。获得的结果如下：1。铬 - 果胶合金通过电lag固定和25个妈妈直径线以及SUS316L不锈钢进行了完善。机械性能得到了很好的满足。2。通过施加电流，在盐水溶液中的SUS316L线上观察到点腐蚀，相反，在604ph的线上没有蚀刻腐蚀。3。为了在操作过程中易于稳定地连接电极与刺激器，开发了连接器和电极尖端的设计。4。将完全植入的FE的原型系统植入了两种材料（SUS316L和604PH）的电极中，并进行了对系统的操作检查。预计开发最终系统的有用信息。