Design of high performance antiviral and antibacterial cold spray coatings for continuous disinfection on high-touch surfaces

高性能抗病毒和抗菌冷喷涂涂层的设计，用于高接触表面的持续消毒

• 批准号: 571026-2021
• 负责人: Yue, StephenS
• 金额: $ 29.14万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=761074
• 关键词: Design; performance; antiviral; antibacterial; cold

The preventive measures currently applied to contain the transmission of SARS-CoV-2 by surfaces (i.e.'fomites') have highlighted the importance of surface disinfection. In order to limit transmission by fomites,most commercial buildings, schools and other public infrastructure have improved their cleaning and disinfection protocols and increased their frequencies, adding financial and logistical burdens to their operation. Therefore, there is a high demand for a reliable and economical solution that would provide passive and continuous disinfection on frequently touched surfaces. This project aims to continue our efforts, initiated in a project funded by a CRSNG-COVID-19 grant, in the design of high performance antiviral coatings for frequently touched surfaces. The research will focus on (1) the development of knowledge on the influence of properties of copper-based materials on the mechanisms of inactivation of viruses and bacteria to develop coatings with enhanced activities against a wide range of viruses and bacteria and (2) develop coatings that maintain their antiviral and antibacterial performance for years by withstanding normal conditions of use, including cleaning and disinfection protocols that use harsh chemicals. The project partners include McGill University, supplying Materials and Virus and Bacteria expertise, INRS bringing knowledge of surface interactions and NRC, working with McGill and INRS on materials and processing developments and helping the three collaborating companies industrialize and commercialize the findings. During the project, the powder company, 5N Plus will develop, based on the results obtained, a metallic powder having the composition and the properties optimal for the marketing of this application; Polycontrols will manufacture industrial demonstrations of the coating technology, produce coatings and commercialize coating systems for this application; Hatch Ltd. will respond to market demands with performance data and sustainability analysis, allowing it to upgrade public infrastructures with such coatings.

目前用于遏制 SARS-CoV-2 通过表面（即“污染物”）传播的预防措施凸显了表面消毒的重要性。为了限制污染物传播，大多数商业建筑、学校和其他公共基础设施都改进了清洁和消毒方案并增加了频率，这增加了其运营的财务和后勤负担。因此，迫切需要一种可靠且经济的解决方案，能够对经常接触的表面提供被动和持续的消毒。该项目旨在继续我们在 CRSNG-COVID-19 资助项目中发起的努力，为经常接触的表面设计高性能抗病毒涂层。该研究将侧重于（1）发展铜基材料特性对病毒和细菌灭活机制影响的知识，以开发对多种病毒和细菌具有增强活性的涂层；（2）开发通过承受正常使用条件（包括使用刺激性化学品的清洁和消毒方案），能够多年保持其抗病毒和抗菌性能的涂层。该项目合作伙伴包括提供材料和病毒和细菌专业知识的麦吉尔大学，提供表面相互作用和 NRC 知识的 INRS，与麦吉尔和 INRS 合作进行材料和加工开发，并帮助三个合作公司将研究成果工业化和商业化。在该项目期间，粉末公司 5N Plus 将根据获得的结果开发一种金属粉末，其成分和性能最适合该应用的营销； Polycontrols 将进行涂层技术的工业演示，生产涂层并将该应用的涂层系统商业化； Hatch Ltd. 将通过性能数据和可持续性分析来响应市场需求，从而利用此类涂料升级公共基础设施。