Partitioning of dietary methionine sources toward protein and non-protein fates during lactation in sows

母猪哺乳期间日粮蛋氨酸来源对蛋白质和非蛋白质命运的分配

基本信息

批准号：
577259-2022
负责人：
Huber, LeeAnneLE
金额：
$ 6.28万
依托单位：
University of Guelph
依托单位国家：
加拿大
项目类别：
Alliance Grants
财政年份：
2022
资助国家：
加拿大
起止时间：
2022-01-01 至 2023-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=743535
关键词：
Partitioning dietary methionine sources toward

项目摘要

Pre-weaning mortality is a major welfare concern for pigs and represents a significant loss of revenue for industry stakeholders. Methionine is an indispensable amino acid for lactating sows, necessary for protein synthesis but also for the biosynthesis of cysteine and taurine, and is the major methyl donor in the body to generate additional essential non-protein molecules like creatine and phosphatidylcholine. Research in the area of optimal dietary methionine level and source for lactating sows to maximize milk output and offspring quality is scarce. Current feeding recommendations are based on historical sow requirement estimates developed in times of lower production capacity and not considering extra-protein roles of amino acids, nor the effects on milk production or offspring quality and survivability. This research partnership will explore the effects of different dietary methionine sources on milk production and offspring survivability and growth, the partitioning of methionine between protein and non-protein fates within the lactating sow, and ultimately, generate practical methionine feeding recommendations for lactating sows. The data generated herein will also be useful for future modifications to nutrient requirements models for lactating sows. The benefits of improving sow milk production capacity by supplying the ideal dietary methionine level and source include improving sow and offspring performance, reducing the environmental footprint of pork production by maximizing the kilograms of pork produced per sow, reducing nitrogen losses from pig farms, and increasing farm profitability and the economic vitality of the Canadian swine industry.

断奶前死亡率是猪的主要福利问题，并且给行业利益相关者带来了巨大的收入损失。蛋氨酸是哺乳母猪不可缺少的氨基酸，是蛋白质合成所必需的，也是半胱氨酸和牛磺酸的生物合成所必需的，并且是体内产生其他必需非蛋白质分子（如肌酸和磷脂酰胆碱）的主要甲基供体。关于泌乳母猪的最佳日粮蛋氨酸水平和来源以最大限度地提高产奶量和后代质量的研究很少。目前的饲喂建议是基于历史母猪需求估算，在生产能力较低时制定，没有考虑氨基酸的额外蛋白质作用，也没有考虑对产奶量或后代质量和生存能力的影响。该研究合作伙伴关系将探讨不同日粮蛋氨酸来源对产奶量、后代存活率和生长的影响、泌乳母猪体内蛋氨酸在蛋白质和非蛋白质命运之间的分配，并最终为泌乳母猪提供实用的蛋氨酸喂养建议。本文生成的数据也可用于将来修改泌乳母猪营养需求模型。通过提供理想的日粮蛋氨酸水平和来源来提高母猪产奶能力的好处包括提高母猪及其后代的生产性能，通过最大限度地提高每头母猪生产的猪肉公斤数来减少猪肉生产的环境足迹，减少养猪场的氮损失，并增加农场盈利能力和加拿大养猪业的经济活力。