Reconstructing the universal tree and network of life

重建宇宙生命之树和网络

• 批准号: FL150100038
• 负责人: Prof Philip Hugenholtz
• 金额: $ 210.76万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Australian Laureate Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-08-01 至 2021-12-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FL150100038
• 关键词: Reconstructing; universal; tree; network; life

Reconstructing the universal tree and network of life: This fellowship project aims to obtain 100 000 genome sequences and systematically organise these into natural phylogenetic relationships comprising both vertical inheritance and lateral transfers. One of the challenges in biology today is to reconstruct the complete evolutionary history of life on Earth. A major hurdle to this goal is our inability to culture most microbial species which comprise the bulk of evolutionary diversity. The framework developed in this project seeks to replace the current incomplete classification of microorganisms to provide fundamental insights into ecology and evolution. It is hoped that the outcomes of the project can be applied to manage risk and capture opportunities in important Australian industries including agriculture, mining and biotechnology.

重建普遍的生命树和网络：该奖学金项目旨在获得10万个基因组序列，并将其系统地组织成包括垂直遗传和横向转移的自然系统发育关系。当今生物学面临的挑战之一是重建地球上生命的完整进化史。实现这一目标的一个主要障碍是我们无法培养大多数构成进化多样性的微生物物种。该项目开发的框架旨在取代当前不完整的微生物分类，为生态学和进化提供基本见解。希望该项目的成果能够应用于农业、采矿和生物技术等澳大利亚重要行业的风险管理和抓住机遇。