Horticultural and production research of medical plants for EXKA Inc.

EXKA Inc.的药用植物园艺和生产研究

• 批准号: 543704-2019
• 负责人: Lefsrud, Mark
• 金额: $ 7.29万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=692722
• 关键词: Horticultural; production; research; medical; plants

The legal status of cannabis is shifting, causing a rapidly expanding market in North America and Europe. Due to its previous listing as an illicit drug and current status as a controlled substance, knowledge gaps exist in cannabis production and processing. While the number of clinical applications for cannabis is growing, validated methods and internationally recognized guidelines for cannabis production are extremely limited. This lack of standards has resulted in conflicting methods that have led to varied product yield, potency and quality. In Canada, the full legalization of cannabis allows industry and researchers to work together toward standardizing cannabis production, postharvest handling and processing. McGill University is working with EXKA Inc to develop a research program to address some of these challenges that will contribute to the development of optimized methods that will improve medicinal plants (basil, hops and cannabis) during growth through nutrient and fertilizer management, post-harvest processing (drying, grinding, and storage) and extraction of medicinally important cannabis compounds. Poorly understood factors that impact the accumulation of these compounds in plants will be explored. For instance, identifying growth conditions that could influence cannabis compound biosynthesis will allow for improved production that maximizes compound accumulation. Importantly, major objectives include the evaluation of common plant processing, extraction and purification techniques for medicinal-grade cannabis products. Standardized tests will be used to determine if compound yield and/or product quality are affected at any step in the production process.

大麻的法律地位正在发生变化，导致北美和欧洲市场迅速扩大。由于大麻之前被列为非法药物，而目前又被列为受控物质，因此大麻生产和加工方面存在知识差距。尽管大麻的临床应用数量不断增加，但经过验证的方法和国际公认的大麻生产指南却极其有限。标准的缺乏导致方法相互矛盾，从而导致产品产量、功效和质量各异。在加拿大，大麻的全面合法化使工业界和研究人员能够共同努力，实现大麻生产、采后处理和加工的标准化。麦吉尔大学正在与 EXKA Inc 合作开发一项研究计划，以解决其中一些挑战，这将有助于开发优化方法，通过营养和肥料管理、收获后改善药用植物（罗勒、啤酒花和大麻）的生长过程。加工（干燥、研磨和储存）和提取具有重要药用价值的大麻化合物。我们将探讨影响这些化合物在植物中积累的人们知之甚少的因素。例如，确定可能影响大麻化合物生物合成的生长条件将有助于提高产量，最大限度地提高化合物积累。重要的是，主要目标包括评估药用级大麻产品的常见植物加工、提取和纯化技术。将使用标准化测试来确定生产过程中任何步骤的化合物产量和/或产品质量是否受到影响。