Development of a novel Shiga toxin inhibitor that targeting of intracellular transport of the toxin
开发一种靶向细胞内毒素转运的新型志贺毒素抑制剂
基本信息
- 批准号：15K08480
- 负责人：
- 金额：$ 3.16万
- 依托单位：
- 依托单位国家：日本
- 项目类别：Grant-in-Aid for Scientific Research (C)
- 财政年份：2015
- 资助国家：日本
- 起止时间：2015-04-01 至 2018-03-31
- 项目状态：已结题
- 来源：
- 关键词：
项目摘要
暂无数据
项目成果
期刊论文数量（5）
专著数量（0）
科研奖励数量（0）
会议论文数量（0）
专利数量（0）
Affinity-based screening of tetravalent peptides identifies subtype-selective neutralizers of Shiga toxin 2d, a highly virulent subtype, by targeting a unique amino acids involved in its receptor recognition.
基于亲和力的四价肽筛选通过靶向参与其受体识别的独特氨基酸来鉴定志贺毒素 2d（一种高毒力亚型）的亚型选择性中和剂。
- DOI：
- 发表时间：2016
- 期刊：
- 影响因子：3.1
- 作者：Mitsui T.;Watanabe-Takahashi M.;Shimizu E.;Zhang B.;Funamoto S.;Yamasaki S.;Nishikawa K.
- 通讯作者：Nishikawa K.
Identification of a Wide Range of Motifs Inhibitory to Shiga Toxin by Affinity-Driven Screening of Customized Divalent Peptides Synthesized on a Membrane
- DOI：10.1128/aem.03517-14
- 发表时间：2015-02-01
- 期刊：
- 影响因子：4.4
- 作者：Kato, Mihoko;Watanabe-Takahashi, Miho;Nishikawa, Kiyotaka
- 通讯作者：Nishikawa, Kiyotaka
共 3 条
- 1
Takahashi Miho其他文献
Abstract 5654: Lymphodepletion induces T cell homeostatic proliferation and augments antitumor effects of PD-1/PD-L1 blockade therapy
摘要 5654：淋巴细胞清除诱导 T 细胞稳态增殖并增强 PD-1/PD-L1 阻断疗法的抗肿瘤作用
- DOI：10.1158/1538-7445.am2017-565410.1158/1538-7445.am2017-5654
- 发表时间：20172017
- 期刊：
- 影响因子：0
- 作者：Masashi Arita;Satoshi Watanabe;Takahashi Miho;Miyuki Sato;Aya Ohtsubo;Kosuke Ichikawa;Rie Kondo;T. Abe;J. Tanaka;T. Koya;T. KikuchiMasashi Arita;Satoshi Watanabe;Takahashi Miho;Miyuki Sato;Aya Ohtsubo;Kosuke Ichikawa;Rie Kondo;T. Abe;J. Tanaka;T. Koya;T. Kikuchi
- 通讯作者：T. KikuchiT. Kikuchi
Clinical Course and Prognosis of Acute Rheumatic Fever with Carditis in Six Patients
急性风湿热合并心脏炎六例临床经过及预后
- DOI：10.9794/jspccs.36.27710.9794/jspccs.36.277
- 发表时间：20202020
- 期刊：
- 影响因子：0
- 作者：Ishiodori Takumi;Horigome Hitoshi;Yano Yusuke;Shima Yuriko;Nozaki Yoshihiro;Ishikawa Nobuyuki;Lin Lisheng;Takahashi Miho;Murakami Takashi;Shiono Junko;Takada HidetoshiIshiodori Takumi;Horigome Hitoshi;Yano Yusuke;Shima Yuriko;Nozaki Yoshihiro;Ishikawa Nobuyuki;Lin Lisheng;Takahashi Miho;Murakami Takashi;Shiono Junko;Takada Hidetoshi
- 通讯作者：Takada HidetoshiTakada Hidetoshi
An analysis of oral microbial flora by T-RFLP in patients undergoing hematopoietic stem cell transplantation
T-RFLP分析造血干细胞移植患者口腔微生物菌群
- DOI：10.1007/s12185-020-02958-y10.1007/s12185-020-02958-y
- 发表时间：20202020
- 期刊：
- 影响因子：2.1
- 作者：Takahashi Miho;Toyosaki Masako;Matsui Keiko;Machida Shinichiro;Kikkawa Eri;Ota Yoshihide;Kaneko Akihiro;Ogawa Yoshiaki;Ando Kiyoshi;Onizuka MakotoTakahashi Miho;Toyosaki Masako;Matsui Keiko;Machida Shinichiro;Kikkawa Eri;Ota Yoshihide;Kaneko Akihiro;Ogawa Yoshiaki;Ando Kiyoshi;Onizuka Makoto
- 通讯作者：Onizuka MakotoOnizuka Makoto
The Mayan Traditional Medicine: Theories and Ethics
玛雅传统医学：理论与伦理
- DOI：
- 发表时间：20182018
- 期刊：
- 影响因子：0
- 作者：Sato Miyuki;Watanabe Satoshi;Tanaka Hiroshi;Nozaki Koichiro;Arita Masashi;Takahashi Miho;Shoji Satoshi;Ichikawa Kosuke;Kondo Rie;Aoki Nobumasa;Hayashi Masachika;Ohshima Yasuyoshi;Koya Toshiyuki;Ohashi Riuko;Ajioka Yoichi;Kikuchi Toshiaki;Mitsuho IkedaSato Miyuki;Watanabe Satoshi;Tanaka Hiroshi;Nozaki Koichiro;Arita Masashi;Takahashi Miho;Shoji Satoshi;Ichikawa Kosuke;Kondo Rie;Aoki Nobumasa;Hayashi Masachika;Ohshima Yasuyoshi;Koya Toshiyuki;Ohashi Riuko;Ajioka Yoichi;Kikuchi Toshiaki;Mitsuho Ikeda
- 通讯作者：Mitsuho IkedaMitsuho Ikeda
Development of a three-dimensional HPLC system for acidic amino acid enantiomers and determination of their amounts in mice lacking D-aspartic acid oxidase activity
酸性氨基酸对映体三维 HPLC 系统的开发及其在缺乏 D-天冬氨酸氧化酶活性的小鼠中的含量测定
- DOI：10.1016/j.jpbao.2023.10000410.1016/j.jpbao.2023.100004
- 发表时间：20232023
- 期刊：
- 影响因子：0
- 作者：Ishii Chiharu;Morinaga Rin;Takahashi Miho;Mita Masashi;Akita Takeyuki;Hamase KenjiIshii Chiharu;Morinaga Rin;Takahashi Miho;Mita Masashi;Akita Takeyuki;Hamase Kenji
- 通讯作者：Hamase KenjiHamase Kenji
共 12 条
- 1
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- 3
Takahashi Miho的其他基金
Development of a new therapeutic agent that inhibits the production of exosome-associated Shiga toxin 2
开发一种抑制外泌体相关志贺毒素 2 产生的新治疗剂
- 批准号：18K0712818K07128
- 财政年份：2018
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research (C)Grant-in-Aid for Scientific Research (C)
A corpus-based semantic-syntactic analysis of the co-occurrence of motion verbs and path expressions in German
基于语料库的德语运动动词与路径表达共现的语义句法分析
- 批准号：17K1344117K13441
- 财政年份：2017
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Young Scientists (B)Grant-in-Aid for Young Scientists (B)
Development of a multi-assessment scale and psychoeducational program for adults with Autism Spectrum Disorder for team support.
为患有自闭症谱系障碍的成年人制定多重评估量表和心理教育计划，以获取团队支持。
- 批准号：16K0434516K04345
- 财政年份：2016
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research (C)Grant-in-Aid for Scientific Research (C)
The Development and Evaluation of a Psychological Support Program for the Unemployed - for the Integration of Foreign Practice and Japanese Culture
失业者心理支持项目的开发与评估——外国实践与日本文化的融合
- 批准号：2340205723402057
- 财政年份：2011
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research (B)Grant-in-Aid for Scientific Research (B)
相似海外基金
Marine natural products that capture biological brriers
捕获生物屏障的海洋天然产品
- 批准号：19H0304019H03040
- 财政年份：2019
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research (B)Grant-in-Aid for Scientific Research (B)
Molecular mechanism of the high virulence of Stx2 in enterohemorrhagic E. coli infections.
Stx2在肠出血性大肠杆菌感染中高毒力的分子机制。
- 批准号：2439003524390035
- 财政年份：2012
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research (B)Grant-in-Aid for Scientific Research (B)
Structural study of signal transduction by membrane receptors through protein-protein interactions
膜受体通过蛋白质-蛋白质相互作用进行信号转导的结构研究
- 批准号：1508310215083102
- 财政年份：2003
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research on Priority AreasGrant-in-Aid for Scientific Research on Priority Areas
Phospholipid-nanotube containing a peptide, Hel 13-5, as a model of transport vesicles in cell.
含有肽 Hel 13-5 的磷脂纳米管，作为细胞内运输囊泡的模型。
- 批准号：1557014115570141
- 财政年份：2003
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research (C)Grant-in-Aid for Scientific Research (C)
茎頂根端軸の形成・維持を支配する細胞間相互作用の解析
控制茎尖根轴形成和维持的细胞间相互作用分析
- 批准号：1403620514036205
- 财政年份：2002
- 资助金额：$ 3.16万$ 3.16万
- 项目类别：Grant-in-Aid for Scientific Research on Priority AreasGrant-in-Aid for Scientific Research on Priority Areas