Totally implantable electrodes for FES to measure the muscle fatigue by block stimulation

FES 的完全植入式电极通过块刺激测量肌肉疲劳

基本信息

批准号：
09671466
负责人：
SHIMADA Yoichi
金额：
$ 0.9万
依托单位：
Akita University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671466/
关键词：
FES Totally implantable electrode Block stimulation Muscle fatigue

项目摘要

OBJECTIVE : In electrical stimulation, the muscles contract, in order, from the more fatigable motor units to the fatigue resistant motor units (reverse recruitment). Block stimulation is a method by which to recruitment in the physiological order in electrical stimulation. The purpose of this study were to develop the totally implantabel electrodes and to evaluate the effects of low frequency block stimulation of the sciatic nerve on the medial gastrocnemius muscle of rats an effort to reduce the muscle fatigue using this original electrode.MATERIALS : Ten extremities of nine Wistar rats were used. We isometrically measured the contraction force of the medial head of the gastrocnemius muscle of the rats.METHODS : The frequency of drive stimulation was set at 100Hz. The block stimulation frequency was set at 20, 50 or 100Hz for each of three groups. Drive stimulation was applied for 20 sec, and then 2 sec later, block stimulation was superimposed for 15 sec. We measured maximal tetanic force at 2.4, 6, 10 and 14 sec, and calculated the strength decrement index at 6, 10 and 14 sec to yield the attenuation of muscle force from 2.4 sec to each of 6, 10 and 14 sec.RESULTS : Block effect was seen at all three block stimulation frequencies. Muscle fatigue under block stimulation was significantly less at both 50 and 100Hz block stimulation frequencies than due to drive stimulation only (p<0.05).CONCLUSION : These results suggest that block stimulation is a more favorable method by which to reduce muscle fatigue during clinical use of functional electrical stimulation.

目的：在电刺激中，肌肉从更疲劳的电动机单元到抗疲劳运动单元（反向募集）收缩。块刺激是一种在电刺激中以生理顺序募集的方法。这项研究的目的是开发完全植入的电极，并评估坐骨神经刺激对大鼠内侧胃gas肌的低频刺激的影响，以使用这种原始电极来减轻肌肉疲劳。我们近乎测量了大鼠腹骨肌内侧的收缩力。方法：驱动刺激的频率设置为100Hz。三组中的每一组设置为20、50或100Hz的块刺激频率。将驱动刺激施加20秒，然后在2秒之后施加驱动刺激，将块刺激叠加15秒。我们测量了2.4、6、10和14秒时的最大四烷基力，并计算了6、10和14秒的强度降低指数，从而从2.4秒到6、10和14秒的每种肌肉力量的衰减。在所有三个块刺激频率下都可以看到块效应：块效应。在50和100Hz刺激频率下，在块刺激下的肌肉疲劳明显少于仅驱动刺激（p <0.05）。结论：这些结果表明，在功能电刺激的临床使用过程中，通过减少肌肉疲劳的方法是一种更有利的方法。