Multibody dynamic modeling of the upper limb for the quantification of muscle force co-contraction and synergy strategies during motion

上肢多体动力学建模，用于量化运动过程中的肌肉力量协同收缩和协同策略

• 批准号: 402002-2013
• 负责人: Raison, Maxime
• 金额: $ 1.75万
• 依托单位: École Polytechnique de Montréal
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=662915
• 关键词: Multibody; dynamic; modeling; upper; limb

The goal of this biomedical engineering research program is to quantify individual muscle forces during upper limb motion in healthy adults. This will also enable to explain the temporal evolution of muscle strategies of co-contraction, i.e. opposite actions of muscles on each side of a joint, and synergy, i.e. joint actions of muscles on the same side of a joint, for fundamental knowledge and future innovative applications in sports, robotics, rehabilitation, orthopedics, ergonomics and/or prevention. The program includes 3 specific objectives: 1. Develop a biofidelic and personalized dynamic model of the upper limb, enabling to quantify muscle forces during motion. 2. Validate it as far as possible using nerve motor blocs, i.e. locally anesthetizing selected muscles. 3. Use it to understand the muscle overactuation strategies during flexion/extension, pronation/supination, and pointing task.**The novelty of this research program is double:**1. The goal will be achieved through a unique scientific approach based on the development of a biofidelic and personalized dynamic method assessing the muscle forces in the human body in motion.**2. This objective of improving the understanding of muscle overactuation in the human body during motion is completely innovant in literature and of great interest concerning current demands for personalized muscle force quantification in the clinical and industrial domains. The main fields of applications will be rehabilitation and orthopedic domain for the evaluation and follow-up of musculo-skeletal pathologies and the design of assistive device, and the sport domain for the analysis and improvement of athletic performance. The trainingship of undergraduate and graduate students is a fundamental part of this multi-disciplinary research program, which will allow them to develop strong skills in applied mechanics (biomechanical modeling, multibody dynamics) and experimentation (design of experimental protocol, analyses of error, reproducibility and sensitivity). Finally, this research program will also enable to develop international collaborations.******************

该生物医学工程研究项目的目标是量化健康成年人上肢运动期间的个体肌肉力量。这也将能够解释肌肉协同收缩策略（即关节两侧肌肉的相反动作）和协同作用（即关节同一侧肌肉的联合动作）的时间演变，以供基础知识和未来使用。体育、机器人、康复、骨科、人体工程学和/或预防方面的创新应用。该计划包括 3 个具体目标： 1. 开发上肢的生物逼真和个性化动态模型，能够量化运动过程中的肌肉力量。 2. 尽可能使用神经运动块进行验证，即局部麻醉选定的肌肉。 3. 用它来了解屈曲/伸展、旋前/旋后和指向任务期间的肌肉过度致动策略。**该研究项目的新颖性是双重的：**1。该目标将通过一种独特的科学方法来实现，该方法基于生物忠实和个性化动态方法的开发，用于评估运动中人体的肌肉力量。**2。这种提高对运动过程中人体肌肉过度致动的理解的目标在文献中完全是创新的，并且对于当前临床和工业领域中个性化肌肉力量化的需求非常有趣。主要应用领域是康复和骨科领域，用于肌肉骨骼病理的评估和随访以及辅助装置的设计，以及运动领域，用于分析和提高运动表现。本科生和研究生的培训是这个多学科研究计划的基本组成部分，这将使他们能够发展应用力学（生物力学建模、多体动力学）和实验（实验方案设计、误差分析、再现性）方面的强大技能。和灵敏度）。最后，该研究计划还将促进国际合作的发展。********************