Assessing Bone Quality and Health: Experimental imaging, structural characterisation, and mechanical modelling of bone in 3D

评估骨骼质量和健康：实验成像、结构表征和 3D 骨骼机械建模

• 批准号: DP0452646
• 负责人: Prof Mark Knackstedt
• 金额: $ 29.6万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-06-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0452646
• 关键词: Assessing; Bone; Quality; Health; Experimental

Age-related bone fractures due to osteoporosis impose a significant social and economic problem on our increasingly aging population. The assessment of bone quality is important in the diagnosis of age related bone fragility and for studying the efficacy of therapeutic intervens. In this proposal a unique interdisciplinary group with expertise in bone and mineral research, experimental 3D imaging and the characterisation and modelling of complex materials will tackle the problem of assessing bone quality and health. The proposed research will greatly improve our assessment of the mechanical competence of bone.

骨质疏松症导致的与年龄相关的骨折给日益老龄化的人口带来了重大的社会和经济问题。骨质量的评估对于年龄相关骨脆性的诊断和研究治疗干预的功效非常重要。在该提案中，一个独特的跨学科小组在骨骼和矿物质研究、实验 3D 成像以及复杂材料的表征和建模方面拥有专业知识，将解决评估骨骼质量和健康的问题。拟议的研究将极大地改善我们对骨骼机械能力的评估。