The comprehensive identification of transcription factors associated with anti-atherosclerotic effects of polyphenols and the clarification of the mechanisms

多酚抗动脉粥样硬化作用相关转录因子的全面鉴定及机制的阐明

• 批准号: 17K17923
• 负责人: KANOH Naomi
• 金额: $ 2.66万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2017
• 资助国家: 日本
• 起止时间: 2017-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17K17923/
• 关键词: 機能性食品成分; ポリフェノール; 動脈硬化; 転写因子; スクリーニング; マクロファージ; TMT解析; 2D-DIGE; プロテオーム解析

项目成果

Benzyl isothiocyanate attenuates the hydrogen peroxide-induced interleukin-13 expression through glutathione S-transferase P induction in T lymphocytic leukemia cells

异硫氰酸苄酯通过谷胱甘肽 S-转移酶 P 诱导 T 淋巴细胞白血病细胞减弱过氧化氢诱导的白细胞介素 13 表达

• DOI: 10.1002/jbt.22054
• 发表时间: 2018
• 期刊: Journal of Biochemical and Molecular Toxicology
• 影响因子: 3.6
• 作者: Tang Yue;Naito Sho;Abe-Kanoh Naomi;Ogawa Seiji;Yamaguchi Shu;Zhu Beiwei;Murata Yoshiyuki;Nakamura Yoshimasa
• 通讯作者: Nakamura Yoshimasa

The effects of resveratrol and piceid on macrophage efferocytosis

白藜芦醇和piceid对巨噬细胞胞吞作用的影响

• 发表时间: 2019
• 作者: Naomi Kanoh;Yuki Hashimoto;Haruka Yamamoto and Miyuki Uemura
• 通讯作者: Haruka Yamamoto and Miyuki Uemura

Benzyl isothiocyanate ameliorates acetaldehyde-induced cytotoxicity by enhancing aldehyde dehydrogenase activity in murine hepatoma Hepa1c1c7 cells

• DOI: 10.1016/j.fct.2017.08.016
• 发表时间: 2017-10-01
• 期刊: FOOD AND CHEMICAL TOXICOLOGY
• 影响因子: 4.3
• 作者: Liu, Yujia;Yamanaka, Momoko;Nakamura, Yoshimasa
• 通讯作者: Nakamura, Yoshimasa

Inhibition of phosphatidylinositide 3-kinase impairs the benzyl isothiocyanate-induced accumulation of autophagic molecules and Nrf2 in human colon cancer cells

• DOI: 10.1080/09168451.2017.1374830
• 发表时间: 2017-09
• 期刊: Bioscience, Biotechnology, and Biochemistry
• 作者: Xiaoyang Liu;Naomi Abe-Kanoh;Yujia Liu;B. Zhu;S. Munemasa;Toshiyuki Nakamura;Y. Murata;Yoshimasa Nakamura

Sesamin Catechol Glucuronides Exert Anti-inflammatory Effects by Suppressing Interferon β and Inducible Nitric Oxide Synthase Expression through Deconjugation in Macrophage-like J774.1 Cells

• DOI: 10.1021/acs.jafc.8b07227
• 发表时间: 2019-07-10
• 期刊: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
• 影响因子: 6.1
• 作者: Abe-Kanoh, Naomi;Kunimoto, Yumi;Kawai, Yoshichika
• 通讯作者: Kawai, Yoshichika