Elucidating the importance of endothelium-dependent hyperpolarization in the pathogenesis of microvascular angina

阐明内皮依赖性超极化在微血管心绞痛发病机制中的重要性

• 批准号: 17K15983
• 负责人: Shiroto Takashi
• 金额: $ 2.58万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2017
• 资助国家: 日本
• 起止时间: 2017-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17K15983/
• 关键词: 内皮機能障害; 微小血管狭心症; 内皮由来弛緩因子; 内皮由来過分極因子; EDHF; 分子心臓学

项目成果

Marked Impairment of Endothelium-dependent Digital Vasodilatations in Patients with Microvascular Angina -Possible Manifestation of Systemic Small Artery Disease-

微血管心绞痛患者内皮依赖性指血管舒张的显着损害 -系统性小动脉疾病的可能表现 -

• 发表时间: 2019
• 作者: Shoko Kajitani;Takashi Shiroto;Shigeo Godo;Akiyo Ito;Yosuke Ikumi;Koichi Sato;Jun Sugisawa;Satoshi Tsuchiya;Akira Suda;Tomohiko Shindo;Shohei Ikeda; Kiyotaka Hao;Yoku Kikuchi;Kotaro Nochioka;Yasuharu Matsumoto;Jun Takahashi;Hiroaki Shimoka
• 通讯作者: Hiroaki Shimoka

Marked impairment of endothelium-dependent digital vasodilatations in patients with microvascular angina compared with those with vasospastic angina

与血管痉挛性心绞痛患者相比，微血管性心绞痛患者的内皮依赖性指血管舒张功能明显受损

• 发表时间: 2019
• 作者: Shoko Kajitani;Takashi Shiroto;Shigeo Godo;Akiyo Ito;Yosuke Ikumi;Koichi Sato;Jun Sugisawa; Satoshi Tsuchiya;Akira Suda;Tomohiko Shindo;Shohei Ikeda;Kiyotaka Hao;Yoku Kikuchi; Kotaro Nochioka;Yasuharu Matsumoto;Jun Takahashi;Hiroaki Shimok
• 通讯作者: Hiroaki Shimok

Marked impairment of endothelium-dependent digital vasodilatations in patients with microvascular angina compared with those with vasospastic angina

与血管痉挛性心绞痛患者相比，微血管性心绞痛患者的内皮依赖性指血管舒张功能明显受损

• 发表时间: 2019
• 作者: Shoko Kajitani;Takashi Shiroto;Shigeo Godo;Akiyo Ito;Yosuke Ikumi;Koichi Sato;Jun Sugisawa;Satoshi Tsuchiya;Akira Suda;Tomohiko Shindo;Shohei Ikeda; Kiyotaka Hao;Yoku Kikuchi;Kotaro Nochioka;Yasuharu Matsumoto;Jun Takahashi;Hiroaki Shimoka
• 通讯作者: Hiroaki Shimoka

Marked impairment of endothelium-dependent digital vasodilatations in patients with microvascular angina compared with those with vasospastic angina

与血管痉挛性心绞痛患者相比，微血管性心绞痛患者的内皮依赖性指血管舒张功能明显受损

• 发表时间: 2019
• 作者: Shoko Kajitani;Takashi Shiroto;Shigeo Godo;Akiyo Ito;Yosuke Ikumi;Koichi Sato;Jun Sugisawa;Satoshi Tsuchiya;Akira Suda;Tomohiko Shindo;Shohei Ikeda;Kiyotaka Hao;Yoku Kikuchi;Kotaro Nochioka;Yasuharu Matsumoto; Jun Takahashi;Hiroaki Shimoka
• 通讯作者: Hiroaki Shimoka

指先から見えた微小血管狭心症患者の新たな病態 - 全身の微小血管の機能障害を反映 -

通过指尖看到的微血管心绞痛患者的新病理 - 反映全身微血管功能障碍 -