Development of Concerto Molecular Catalysts for Practical Catalysis

实用催化协奏曲分子催化剂的开发

• 批准号: 18065007
• 负责人: IKARIYA Takao
• 金额: $ 84.86万
• 依托单位: Tokyo Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18065007/
• 关键词: 均一・不均一触媒; 触媒・化学プロセス; 有機工業化学; 合成化学; 均一系触媒; 不均一系触媒

Thanks to conceptually new bifunctional molecular catalysts based on Metal-ligand cooperating effect, we could successfully develop highly efficient asymmetric hydrogenation of polar functionalities which cannot easily hydrogenated by conventional homogeneous catalysts, aerobic oxidation of alcohols in which O2 serves as an excellent hydrogen acceptor, asymmetric C-N and C-C bond forming reactions. The concept of bifunctionality established in the mononuclear complex systems could be applied to bifunctional binuclear metal systems.

得益于基于金属-配体协同效应的新型双功能分子催化剂，我们成功开发了常规均相催化剂不易氢化的极性官能团的高效不对称氢化、以O2作为优良氢受体的醇的有氧氧化、不对称C-N 和 C-C 键形成反应。在单核复杂体系中建立的双功能概念可以应用于双功能双核金属体系。

项目成果

Enantioselective direct amination of α-cyanoacetates catalyzed by bifunctional chiral Ru and Ir amido complexes

• DOI: 10.1021/ja710273s
• 发表时间: 2008-02-20
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Hasegawa, Yasuharu;Watanabe, Masahito;Ikariya, Takao
• 通讯作者: Ikariya, Takao

Acid-Base Bifunction and Umpolung of Bridging Hydride in Coordinatively Unsatruated Meslimido- and Hydrido-Bridged Diiridium Complex.

配位不饱和甲磺酰亚胺和氢桥联二铱配合物中桥联氢化物的酸碱双功能和反极性。

• 发表时间: 2008
• 期刊: Organometallics 27
• 作者: H. Arita;K. Ishiwata;S. KUwata;T. IKariya
• 通讯作者: T. IKariya

Carboxylative cyclization of propargylamines with supercritical carbon dioxide Yoshihito Kayaki

超临界二氧化碳对炔丙胺进行羧基环化 Yoshihito Kayaki

• 发表时间: 2006
• 期刊: Green Chem. 8
• 作者: Masashi Yamamoto;Tomoyuki Suzuki;Takao Ikariya
• 通讯作者: Takao Ikariya

Cycilization of Propargyl AIcohols in Supercritical Carbon Dioxide.

丙炔醇在超临界二氧化碳中的环化。

• 发表时间: 2007
• 期刊: J. Org. Chem. 72
• 作者: Y. Kayaki;M. Yamamoto;T. Ikariya
• 通讯作者: T. Ikariya

Amorphous nano-structured silicas for high-performance carbon dioxide confinement.Shinichiro Ichikawa

用于高性能二氧化碳封存的无定形纳米结构二氧化硅。Shinichiro Ichikawa

• 发表时间: 2010
• 期刊: J.Mater.Chem. 20
• 作者: Tsunetake Seki;Mizuki Tada;Yasuhiro Iwasawa;Takao Ikariya
• 通讯作者: Takao Ikariya