Synthesis of Mono-Functional Olefin Metathesis Polymers

单官能烯烃复分解聚合物的合成

• 批准号: 47263954
• 负责人: Professor Dr. Andreas Kilbinger
• 金额: --
• 依托单位: Departement für Chemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2007
• 资助国家: 德国
• 起止时间: 2006-12-31 至 2010-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/47263954?language=en
• 关键词: Synthesis; Mono; Functional; Olefin; Metathesis

The aim of this research proposal is to provide new synthetic routes for the preparation of well-defined mono-end-functional metathesis polymers. Currently, the ring opening metathesis polymerisation (ROMP) allows the synthesis of well-defined polymers from a large pool of functional monomers. The introduction of exactly one well-defined functional end-group, however, is difficult to achieve. While otherwise a very attractive polymerisation technique even for the non-specialist, this drawback has limited its application across interdisciplinary borders. We recently demonstrated a new synthetic approach to overcome this limitation using an easy to follow sacrificial block-copolymer technique. The preliminary work was limited to hydroxy functional groups. Here we propose the development of this approach in order to be able to introduce a variety of functional groups such as amines, thiols or carboxylic acids to the end of a well-define functional polymer. Polymers carrying one type of functional group along the polymer chain while providing a different functionality at the chain end are otherwise difficult to prepare and particularly useful for the synthesis of biomacromolecule conjugates, block copolymers, surfactants, colloids and the functionalisation of surfaces and nano-particles.

本研究计划的目的是为制备明确的单末端功能复分解聚合物提供新的合成路线。目前，开环复分解聚合（ROMP）允许从大量功能单体合成明确的聚合物。然而，引入精确定义的功能端基是很难实现的。尽管即使对于非专业人士来说，聚合技术也是一种非常有吸引力的技术，但这一缺点限制了其跨学科边界的应用。我们最近展示了一种新的合成方法，使用易于遵循的牺牲嵌段共聚物技术来克服这一限制。初步工作仅限于羟基官能团。在这里，我们建议开发这种方法，以便能够将各种官能团（例如胺、硫醇或羧酸）引入到明确的官能聚合物的末端。沿着聚合物链携带一种类型的官能团同时在链端提供不同官能团的聚合物很难制备，并且特别适用于生物大分子缀合物、嵌段共聚物、表面活性剂、胶体的合成以及表面和纳米颗粒的官能化。