Sympathetic skin response evoked by electrical stimulation of the thoracic sympathetic trunk as intraoperative monitor of endoscopic thoracic sympathectomy. -Health-related quality of life among patients with palmer hyperhidrosis who underwent endoscopic

电刺激胸交感干引起的交感皮肤反应作为内镜胸交感神经切除术的术中监测。

• 批准号: 16591544
• 负责人: KAWAI Kouji
• 金额: $ 2.37万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2004
• 资助国家: 日本
• 起止时间: 2004 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16591544/
• 关键词: primary hyperhidrosis; health-related quality of life; SF-36; endoscopic thoracic sympathetectomy; sympathetic skin responce; event related potential; pre; post-operative examination; indication of operation; 交感神経皮膚反応; 前検査・術後検査; 手術適応; 原発性手掌・腋窩

We planed this study in a purpose to identify the thoracic sympathetic trunk more surely and to reduce compensatory sweating that is the main complication of ETS. Sympathetic skin respbnces (SSRs) following electrical stimulation of the thoracic sympathetic trunk were monitored in 36 patients who underwent ETS. SSRs were obtained at the ipsilateral hand with reproducibility in 34 patients. The latency and the amplitude of SSRs ranged from 0.7s to 4.0s and from 0.3mV to 10mV respectively. All patients obtained the presence of SSRs showed the absence of SSRs following electrical stimulation after sympathetectomy. Adequate sympathectomies were achieved in allpatients. No postoperative complications were not encountered. All patients developed compensatory sweating of the trunk, hip, and lower limbs, which didn't need treatments. Intraoperative monitoring of this method is very useful for evaluating the degree of block of thoracic sympathetic trunk in patients with primary palmar hyperhidrosis who undergo ETS.ETS is a curative therapy, but its effect on health-related quality of life has not been studied. The SF-36 Health Survey was used to assess quality of life before operation and after operation in 15 patients underwent ETS at Yamaguchi Univ.Hospital. All patients underwent ETS at the 2^<nd> and 3^<rd> rib or 3^<rd> rib only. ETS was completed in all patients with adequate effects. Compensatory sweating as complication were seen in all patients. There were no severe complications and perioperative deaths. Before ETS, the SF-36 scores were significantly lower than in the general Japanese population, reflecting significant impairment in role-physical, social functioning, and role-emotional. After ETS, the SF-36 scores (0-100scoring) were improved on all scales except for physical functioning and role-emotional. ETS can significantly improve the health-related quality of life in patients with severe palmer hyperhidrosis.

我们计划了这项研究，目的是更肯定地识别胸腔交感神经，并减少ETS的主要并发症的补偿性出汗。在36例接受ETS的患者中，监测了胸部交感神经的电刺激后的交感神经反应（SSR）。在34例患者中，在同侧具有可重复性的同侧，获得了SSR。 SSRS的潜伏期和幅度分别为0.7至4.0，分别从0.3mV到10mV。所有获得SSR存在的患者均显示交感神经切除术后电刺激后不存在SSR。在所有患者中实现了足够的交感神经。未遇到术后并发症。所有患者都出现了不需要治疗的躯干，臀部和下肢的补偿性出汗。该方法的术中监测对于评估经历ETS的原发性棕榈心性增多症患者的胸交交感神经块的程度非常有用。SETS是一种治愈性疗法，但尚未研究其对健康相关的生活质量的影响。 SF-36健康调查用于评估运行前的生活质量，在手术后，在15名患者的手术后，在Yamaguchi Univ.Hospital进行了ETS。所有患者仅在2^<nd>和3^<rd>肋骨或3^<rd>肋骨上接受ET。所有具有足够作用的患者都完成了ETS。在所有患者中都可以看到补偿性出汗为并发症。没有严重的并发症和围手术期死亡。在ETS之前，SF-36的得分明显低于日本总体，这反映了角色 - 物理，社会功能和角色情感的严重损害。在ETS之后，除身体功能和角色情感外，所有尺度上的SF-36分数（0-100分）均得到改善。 ETS可以显着改善严重帕尔默多汗症患者的健康相关生活质量。