Randomized controlled clinical trial for verifying effects of complete dentures with the resilient denture liner on edentulous patients

验证弹性义齿衬垫全口义齿对无牙颌患者效果的随机对照临床试验

• 批准号: 15592071
• 负责人: GUNJI Atsuko
• 金额: $ 2.24万
• 依托单位: Nihon University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2006
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15592071/
• 关键词: complete denture; randomized controlled clinical trial; resilient denture liner; 褥創; 痛み; 軟質裏装剤; 満足度; 咀嚼値; 栄養摂取充足率; 栄養摂取量充足率; 費用対効果; 歯槽骨の吸収量

A randomized controlled parallel clinical trial at the two hospitals was conducted from April 2004 to July 2006. The permuted block method of randomization with a block size of four consisting of,. treatment with RLD by a senior clinician (SC), treatment with RLD by a junior clinician (JC), treatment with ARD by a SC and treatment with ARD by a JC, in a combination of treatments and clinicians groups (treatments=ARD and RLD ; clinicians=JC and SC) was used. Outcomes: a) numbers of sore spots ; b) duration of wearing dentures; c) pain perception ; d) satisfaction ratings; e) masticatory performance ; f) mandibular movement at the lower incisal point during chewing Results Seventy-four patients who had been consecutively sampled (aged 53 to 89 yrs) were randomized for this trial. No significant differences were observed in any of the baseline characteristics between the ARD and RLD. Significant differences in the number of sore spots in the support and border areas for the mandibular mucosa were clearly observed between the RLD and ARD groups. In contrast, there were no differences in the number of sore spots in the frenum area. Furthermore, significant differences in the number of sore spots in the support and border areas for the maxillary mucosa were definitely observed between the JC and SC groups. The RLD wearers were able to wear their dentures an additional day longer than the ARD wearers. Significant differences between the RLD and ARD groups in the maxillary and mandibular pain ratings were observed. There was no significant difference in the masticatory performance and mandibular movement at the lower incisal point during chewing between the ARD and RLD groups.

从2004年4月至2006年7月进行了两家医院的随机对照平行临床试验。置换的随机块方法，其块大小为四个，由四个组成。高级临床医生（SC）对RLD进行治疗，初级临床医生（JC）对RLD进行治疗，通过SC和JC治疗ARD治疗的ARD治疗，治疗和临床医生组的组合（治疗= ARD和RLD）使用临床医生= JC和SC）。结果：a）酸痛的数量； b）穿着假牙的持续时间； c）疼痛感； d）满意度等级； e）咀嚼性能； f）在咀嚼结果期间，下切口点处的下颌运动是连续采样（53至89岁）的七十四名患者。在ARD和RLD之间的任何基线特征中均未观察到显着差异。在RLD和ARD组之间，明确观察到了下颌粘膜的支撑和边界区域的痛点数量的显着差异。相比之下，弗雷纳姆地区的酸痛斑点数量没有差异。此外，JC组和SC组之间肯定会观察到上颌粘膜的支撑和边界区域的痛点数量的显着差异。 RLD佩戴者能够比ARD佩戴者更长的时间穿着假牙。观察到上颌和下颌疼痛等级中RLD和ARD组之间的显着差异。在ARD组和RLD组之间咀嚼期间，咀嚼点的咀嚼性能和下颌运动没有显着差异。

项目成果

In-vivo and in-vitro studies for analysis of mastication in complete denture wearers by using resilient denture liners

使用弹性义齿衬垫分析全口义齿佩戴者咀嚼功能的体内和体外研究

• 发表时间: 2007
• 期刊: International Journal of Oral-Medical Sciences 5(2)
• 作者: Matsuzaka K;Yoshinari M;Kokubu E;Shimono M;Inoue T;Kimoto S;Shinomiya Mayako
• 通讯作者: Shinomiya Mayako

Clinical effects of acrylic resilient denture liners applied to mandibular complete dentures on the alveolar ridge

• DOI: 10.1111/j.1365-2842.2007.01728.x
• 发表时间: 2007-11-01
• 期刊: JOURNAL OF ORAL REHABILITATION
• 影响因子: 2.9
• 作者: Kimoto, S.;Kimoto, K.;Kobayashi, K.
• 通讯作者: Kobayashi, K.

Randomized controlled clinical trial for verifying the effect of silicone-based resilient denture liner on the masticatory function of complete denture wearers

验证有机硅弹性义齿衬垫对全口义齿佩戴者咀嚼功能影响的随机对照临床试验

• 发表时间: 2006
• 期刊: International Journal of Prosthodontics 19
• 作者: 北川 昇;佐藤裕二;郡司敦子;Kimoto S
• 通讯作者: Kimoto S

The effect of wearing complete dentures on a diet and nutrient adequacy in edentulous patients

佩戴全口义齿对无牙颌患者饮食和营养充足的影响

• 发表时间: 2007
• 期刊: Journal of Japanese Society for Masticatory Science and Health Promotion (in press)
• 作者: Matsuzaka K;Yoshinari M;Kokubu E;Shimono M;Inoue T;Kimoto S;Shinomiya Mayako;郡司敦子;Kimoto Suguru;Shinomiya Mayako;Gunji Atsuko
• 通讯作者: Gunji Atsuko

Randomized Controlled Clinical Trial for Verifying the Effects of Silicone Resilient Denture Liner on the Mastication of Complete Denture Wearers

验证硅胶弹性义齿衬垫对全口义齿佩戴者咀嚼效果影响的随机对照临床试验

• 期刊: International Journal of Prosthodontics (印刷中)
• 作者: 北川 昇;佐藤裕二;郡司敦子;Kimoto S;Kimoto Suguru;Kimoto Suguru
• 通讯作者: Kimoto Suguru